球孢子菌病的当前概况

Boro Ryan, Iyer Prema C, Walczak Maciej A

Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA.

Department of Chemistry, University of Colorado, Boulder, CO 80309, USA.

J Fungi (Basel). 2022 Apr 17;8(4):413. doi: 10.3390/jof8040413.

Coccidioidomycosis, also known as Valley fever, is an endemic fungal infection commonly found in the southwestern parts of the United States. However, the disease has seen an increase in both in its area of residency and its prevalence. This review compiles some of the latest information on the epidemiology, current and in-development pharmaceutical approaches to treat the disease, trends and projections, diagnostic concerns, and the overlapping dynamics of coccidioidomycosis and COVID-19, including in special populations. This review provides an overview of the current diagnostic and therapeutic strategies and identifies areas of future development.

球孢子菌病，也称为山谷热，是一种常见于美国西南部的地方性真菌感染。然而，这种疾病的居住区域和流行率都有所增加。本综述汇编了一些关于流行病学、当前及正在研发的治疗该疾病的药物方法、趋势和预测、诊断问题，以及球孢子菌病与新冠肺炎重叠动态（包括特殊人群中的情况）的最新信息。本综述概述了当前的诊断和治疗策略，并确定了未来的发展领域。