Brunyé Tad T
Center for Applied Brain and Cognitive Sciences, School of Engineering, Tufts University, Medford, MA, United States.
Cognitive Science Team, U.S. Army Natick Soldier Research, Development and Engineering Center, Natick, MA, United States.
Front Hum Neurosci. 2018 Jan 9;11:649. doi: 10.3389/fnhum.2017.00649. eCollection 2017.
Transcranial electrical stimulation (tES) uses low intensity current to alter neuronal activity in superficial cortical regions, and has gained popularity as a tool for modulating several aspects of perception and cognition. This mini-review article provides an overview of tES and its potential for modulating spatial processes underlying successful navigation, including spatial attention, spatial perception, mental rotation and visualization. Also considered are recent advances in empirical research and computational modeling elucidating several stable cortical-subcortical networks with dynamic involvement in spatial processing and navigation. Leveraging these advances may prove valuable for using tES, particularly transcranial direct and alternating current stimulation (tDCS/tACS), to indirectly target subcortical brain regions by altering neuronal activity in distant yet functionally connected cortical areas. We propose future research directions to leverage these advances in human neuroscience.
经颅电刺激（tES）使用低强度电流来改变表层皮质区域的神经元活动，并且作为一种调节感知和认知多个方面的工具已受到广泛关注。这篇综述文章概述了tES及其在调节成功导航所依赖的空间过程方面的潜力，包括空间注意力、空间感知、心理旋转和视觉化。还探讨了实证研究和计算建模的最新进展，这些进展阐明了几个稳定的皮质 - 皮质下网络，它们动态参与空间处理和导航。利用这些进展可能对使用tES，特别是经颅直流电刺激和经颅交流电刺激（tDCS/tACS），通过改变远距离但功能相连的皮质区域的神经元活动来间接靶向皮质下脑区具有重要价值。我们提出了未来的研究方向，以利用人类神经科学的这些进展。
