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针对过渡年龄青少年神经性厌食症的家庭式治疗开放试验。

Open Trial of Family-Based Treatment of Anorexia Nervosa for Transition Age Youth.

作者信息

Dimitropoulos Gina, Landers Ashley L, Freeman Victoria, Novick Jason, Garber Andrea, Le Grange Daniel

机构信息

Faculty of Social Work, University of Calgary, Calgary, Alberta.

Virginia Polytechnic Institute & State University, Virginia USA.

出版信息

J Can Acad Child Adolesc Psychiatry. 2018 Jan;27(1):50-61. Epub 2018 Jan 1.

Abstract

OBJECTIVE

This pilot study conducted an open trial of a manualized adaptation to Family-Based Treatment for Transition Age Youth (FBT-TAY) for Anorexia Nervosa (AN). The aims were: (1) determine the acceptability of FBT for TAY; and, (2) establish preliminary effect sizes for the impact of FBT-TAY on eating disorder behaviour and weight restoration.

METHOD

Twenty-six participants across two paediatric and one adult hospital site were recruited to participate. Participants completed the Eating Disorder Examination Questionnaire (EDE-Q) at the start of treatment, the end-of-treatment, and three-month follow-up.

RESULTS

FBT-TAY is an acceptable and feasible treatment to all study therapists as evidenced by their fidelity to the model. FBT-TAY is a feasible and acceptable intervention to transition age youth, given only 27.27% chose treatment as usual over FBT-TAY. Participants presented significant improvement at end-of-treatment and three-months post-treatment (p < .001; ES = 0.34) from baseline on the EDE-Q Global Score. Participants also achieved and maintained weight restoration at the end-of-treatment and three-months post-treatment when compared to baseline (p < .0001, ES = 0.54).

CONCLUSIONS

FBT-TAY, the first manualized AN treatment for TAY, demonstrated feasibility and acceptability with therapists and participants as well as improvement for participants in EDE-Q global score and weight. Given the current dearth of effective treatments for TAY with AN, FBT-TAY is a promising adaptation of FBT. A larger clinical trial with a 12-month follow-up is recommended.

摘要

目的

本试点研究对一种针对神经性厌食症(AN)的、经手册化改编的适合过渡年龄青年的家庭治疗(FBT-TAY)进行了开放试验。目标如下:(1)确定FBT对过渡年龄青年的可接受性;以及(2)确定FBT-TAY对饮食失调行为和体重恢复影响的初步效应大小。

方法

招募了来自两家儿科医院和一家成人医院的26名参与者。参与者在治疗开始时、治疗结束时和三个月随访时完成饮食失调检查问卷(EDE-Q)。

结果

FBT-TAY对所有研究治疗师而言是一种可接受且可行的治疗方法,这一点从他们对该模式的忠诚度得到证明。FBT-TAY对过渡年龄青年来说是一种可行且可接受的干预措施,因为只有27.27%的人选择常规治疗而非FBT-TAY。参与者在治疗结束时和治疗后三个月的EDE-Q全球评分较基线有显著改善(p < .001;效应大小 = 0.34)。与基线相比,参与者在治疗结束时和治疗后三个月也实现并维持了体重恢复(p < .0001,效应大小 = 0.54)。

结论

FBT-TAY是第一种针对过渡年龄青年的经手册化的神经性厌食症治疗方法,在治疗师和参与者中显示出可行性和可接受性,并且参与者在EDE-Q全球评分和体重方面有所改善。鉴于目前缺乏针对患有神经性厌食症的过渡年龄青年的有效治疗方法,FBT-TAY是FBT的一种有前景的改编形式。建议进行一项为期12个月随访的更大规模临床试验。

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