Bencini P L, Montagnino G, Sala F, De Vecchi A, Crosti C, Tarantino A
Dermatologica. 1986;172(1):24-30. doi: 10.1159/000249288.
Sixty-seven out of 100 kidney transplant recipients treated with cyclosporin and methylprednisolone were evaluated for the presence of dermatological manifestations. Only 2 patients had no dermatological lesions; 80% had iatrogenic lesions, 38% infectious, 13% miscellaneous, 3% cancerous lesions, while 28% had cutaneous manifestations related to previous uremic state. Most of the lesions concerned the pilosebaceous unit: hypertrichosis (60%), epidermal cysts (28%), pilar keratosis (21%), acne (15%), folliculitis (12%) and sebaceous hyperplasia (10%). Among infectious manifestations, viral lesions were the most frequent and were very severe in the first month after transplantation. Two patients developed a squamous-cell epithelioma and a probable cutaneous lymphoma, respectively.
对100名接受环孢素和甲基强的松龙治疗的肾移植受者中的67人进行了皮肤病学表现评估。只有2名患者没有皮肤病变；80%有医源性病变，38%有感染性病变，13%有其他病变，3%有癌性病变，而28%有与先前尿毒症状态相关的皮肤表现。大多数病变涉及毛囊皮脂腺单位：多毛症（60%）、表皮囊肿（28%）、毛发角化病（21%）、痤疮（15%）、毛囊炎（12%）和皮脂腺增生（10%）。在感染性表现中，病毒病变最为常见，且在移植后的第一个月非常严重。两名患者分别发生了鳞状细胞上皮瘤和可能的皮肤淋巴瘤。
