Pfaller Michael A
University of Iowa College of Medicine, Iowa City, IA 52242, USA.
University of Iowa College of Public Health, Iowa City, IA 52242, USA.
J Fungi (Basel). 2015 Aug 31;1(2):217-251. doi: 10.3390/jof1020217.
The diagnosis of invasive candidiasis (IC) and cryptococcosis is often complicated by slow and insensitive culture-based methods. Such delay results in poor outcomes due to the lack of timely therapeutic interventions. Advances in serological, biochemical, molecular and proteomic approaches have made a favorable impact on this process, improving the timeliness and accuracy of diagnosis with resultant improvements in outcome. This paper will serve as an overview of recent developments in the diagnostic approaches to infections due to these important yeast-fungi.
侵袭性念珠菌病（IC）和隐球菌病的诊断常常因基于培养的方法缓慢且不敏感而变得复杂。由于缺乏及时的治疗干预，这种延迟会导致不良后果。血清学、生物化学、分子和蛋白质组学方法的进展对这一过程产生了积极影响，提高了诊断的及时性和准确性，从而改善了治疗结果。本文将概述这些重要酵母真菌所致感染诊断方法的最新进展。
