Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.
Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, Texas 78504, United States.
Bioconjug Chem. 2020 Sep 16;31(9):2021-2045. doi: 10.1021/acs.bioconjchem.0c00323. Epub 2020 Aug 12.
The coronavirus disease 2019 (COVID-19) has dramatically challenged the healthcare system of almost all countries. The authorities are struggling to minimize the mortality along with ameliorating the economic downturn. Unfortunately, until now, there has been no promising medicine or vaccine available. Herein, we deliver perspectives of nanotechnology for increasing the specificity and sensitivity of current interventional platforms toward the urgent need of quickly deployable solutions. This review summarizes the recent involvement of nanotechnology from the development of a biosensor to fabrication of a multifunctional nanohybrid system for respiratory and deadly viruses, along with the recent interventions and current understanding about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
2019 年冠状病毒病（COVID-19）极大地挑战了几乎所有国家的医疗体系。当局正在努力尽量减少死亡率，并改善经济下滑。不幸的是，到目前为止，还没有有效的药物或疫苗。在此，我们从生物传感器的开发到多功能纳米杂化系统的制造，为当前介入平台的快速可部署解决方案提供了纳米技术的应用前景。本综述总结了纳米技术在呼吸和致命病毒方面的最新进展，包括最近的干预措施和对严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）的最新认识。
