Passi Deepak, Bhanot Prateek, Kacker Dhruv, Chahal Deepak, Atri Mansi, Panwar Yoshi
Department of Oral and Maxillofacial Surgery, Inderprastha Dental College and Hospital, Sahibabad, Ghaziabad, India.
Department of Anaesthesiology, Fortis Hospital, Noida, Uttar Pradesh, India.
Natl J Maxillofac Surg. 2017 Jul-Dec;8(2):89-94. doi: 10.4103/njms.NJMS_32_17.
Oral submucous fibrosis (OSMF) is an oral precancerous condition characterized by inflammation and progressive fibrosis of the submucosal tissues resulting in marked rigidity and trismus. OSMF still remains a dilemma to the clinicians due to elusive pathogenesis and less well-defined classification systems. Over the years, many classification systems have been documented in medical literature based on clinical, histopathological, or functional aspects. However, none of these classifications have achieved universal acceptance. Each classification has its own merits and demerits. An attempt is made to provide and update the knowledge of classification system of OSMF so that it can assist the clinicians, beneficial in researches and academics in categorizing this potentially malignant disease for early detection, prompt management, and reducing the mortality. Along with this, pathogenesis and management have also been discussed.
口腔黏膜下纤维化（OSMF）是一种口腔癌前病变，其特征为黏膜下组织的炎症和进行性纤维化，导致明显的僵硬和牙关紧闭。由于发病机制难以捉摸且分类系统不够明确，OSMF对临床医生来说仍然是一个难题。多年来，医学文献中基于临床、组织病理学或功能方面记录了许多分类系统。然而，这些分类都没有得到普遍认可。每种分类都有其优缺点。本文旨在提供并更新OSMF分类系统的知识，以便协助临床医生，有利于对这种潜在恶性疾病进行分类，从而实现早期检测、及时治疗并降低死亡率。与此同时，还讨论了发病机制和治疗方法。
