Elmasry Shady S, Asfour Shihab S, Travascio Francesco
Biomechanics Research Laboratory, Department of Industrial Engineering, University of Miami, 1251 Memorial Drive, McArthur Engineering Building, #156, Coral Gables, FL 33146 e-mail: .
Biomechanics Research Laboratory, Department of Industrial Engineering, University of Miami, 1251 Memorial Drive, McArthur Engineering Building, #268, Coral Gables, FL 33146 e-mail: .
J Biomech Eng. 2018 Jun 1;140(6). doi: 10.1115/1.4039174.
Percutaneous pedicle screw fixation (PPSF) is a well-known minimally invasive surgery (MIS) employed in the treatment of thoracolumbar burst fractures (TBF). However, hardware failure and loss of angular correction are common limitations caused by the poor support of the anterior column of the spine. Balloon kyphoplasty (KP) is another MIS that was successfully used in the treatment of compression fractures by augmenting the injured vertebral body with cement. To overcome the limitations of stand-alone PPSF, it was suggested to augment PPSF with KP as a surgical treatment of TBF. Yet, little is known about the biomechanical alteration occurred to the spine after performing such procedure. The objective of this study was to evaluate and compare the immediate post-operative biomechanical performance of stand-alone PPSF, stand-alone-KP, and KP-augmented PPSF procedures. Novel three-dimensional (3D) finite element (FE) models of the thoracolumbar junction that describes the fractured spine and the three investigated procedures were developed and tested under mechanical loading conditions. The spinal stiffness, stresses at the implanted hardware, and the intradiscal pressure at the upper and lower segments were measured and compared. The results showed no major differences in the measured parameters between stand-alone PPSF and KP-augmented PPSF procedures, and demonstrated that the stand-alone KP may restore the stiffness of the intact spine. Accordingly, there was no immediate post-operative biomechanical advantage in augmenting PPSF with KP when compared to stand-alone PPSF, and fatigue testing may be required to evaluate the long-term biomechanical performance of such procedures.
经皮椎弓根螺钉固定术(PPSF)是一种用于治疗胸腰椎爆裂骨折(TBF)的著名微创手术(MIS)。然而,硬件故障和角度矫正丢失是由脊柱前柱支撑不足引起的常见局限性。球囊后凸成形术(KP)是另一种微创手术,通过用骨水泥增强受伤椎体成功用于治疗压缩性骨折。为了克服单纯PPSF的局限性,有人建议用KP增强PPSF作为TBF的手术治疗方法。然而,对于进行这种手术后脊柱发生的生物力学改变知之甚少。本研究的目的是评估和比较单纯PPSF、单纯KP和KP增强PPSF手术术后即刻的生物力学性能。开发了描述骨折脊柱和三种研究手术的胸腰段连接的新型三维(3D)有限元(FE)模型,并在机械加载条件下进行测试。测量并比较了脊柱刚度、植入硬件处的应力以及上下节段的椎间盘内压力。结果表明,单纯PPSF和KP增强PPSF手术之间测量参数无重大差异,并表明单纯KP可恢复完整脊柱的刚度。因此,与单纯PPSF相比,用KP增强PPSF术后即刻没有生物力学优势,可能需要进行疲劳测试来评估此类手术的长期生物力学性能。