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急性A型主动脉夹层主动脉根部和弓部修复的简单有效方法的短期结果。

Short-term outcomes of a simple and effective approach to aortic root and arch repair in acute type A aortic dissection.

机构信息

Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.

Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.

出版信息

J Thorac Cardiovasc Surg. 2018 Apr;155(4):1360-1370.e1. doi: 10.1016/j.jtcvs.2017.11.089. Epub 2017 Dec 16.

Abstract

OBJECTIVE

To evaluate short-term outcomes following direct aortic root and arch repair in patients with acute type A aortic dissection (ATAAD) without technical adjuncts.

METHODS

Between 2012 and 2016, 94 consecutive patients with ATAAD underwent surgical repair, including aortic root repair (n = 45), root replacement (n = 39), or no root procedure (n = 10). Aortic root repair was achieved by running approximation of the dissected aortic wall circumferentially at the sinotubular junction and reinforcing the coronary ostia with 5-0 Prolene. The aortic root and arch were anastomosed to the Dacron graft with 5-0 Prolene without Teflon felt or biological glue.

RESULTS

Postoperative new-onset myocardial infarction, stroke, renal failure, and complete heart block occurred in 0%, 4%, 13%, and 0% of patients, respectively, whereas 30-day mortality was 4%. The incidences of permanent neurologic deficit and renal failure were 1% and 2%, respectively. Up to 5 years, the aortic root repair group was free from residual or recurrent aortic root dissection, major change in the aortic root diameter, and moderate to severe aortic regurgitation; the entire cohort was free of anastomotic pseudoaneurysm and reoperation for proximal aortic pathology or significant change in diameter of the aortic arch and descending thoracic aorta. Overall survival was 85% at 4 years and was significantly enhanced in the aortic root repair group compared with the Bentall group (n = 24) (93% vs 57%; P = .035).

CONCLUSIONS

Direct aortic root and arch repair with approximation of the aortic wall without use of technical adjuncts is safe and effective for patients with ATAAD. If warranted, preservation of the native aortic valve should be considered for a potential survival benefit.

摘要

目的

评估不使用技术辅助直接进行主动脉根部和弓部修复的急性 A 型主动脉夹层(ATAAD)患者的短期转归。

方法

2012 年至 2016 年,94 例 ATAAD 患者接受了手术修复,其中主动脉根部修复(n=45)、根部置换(n=39)或不进行根部手术(n=10)。主动脉根部修复是通过在窦管交界处环绕性地使夹层主动脉壁靠拢,并用 5-0 Prolene 加固冠状动脉口来实现的。主动脉根部和弓部用 5-0 Prolene 与 Dacron 移植物吻合,不使用 Teflon 毡或生物胶。

结果

术后新发心肌梗死、卒中和肾衰竭、完全性心脏传导阻滞的发生率分别为 0%、4%、13%和 0%,而 30 天死亡率为 4%。永久性神经功能缺损和肾衰竭的发生率分别为 1%和 2%。5 年时,主动脉根部修复组无残余或复发性主动脉根部夹层、主动脉根部直径的主要变化和中重度主动脉瓣反流;整个队列无吻合口假性动脉瘤、近端主动脉病变或主动脉弓和降胸主动脉直径的显著变化需要再次手术。4 年时的总体生存率为 85%,主动脉根部修复组明显高于 Bentall 组(n=24)(93% vs 57%;P=.035)。

结论

不使用技术辅助直接进行主动脉根部和弓部修复,用主动脉壁靠拢的方法治疗 ATAAD 患者是安全有效的。如果有必要,应考虑保留原生主动脉瓣,以获得潜在的生存获益。

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