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原发性甲状旁腺功能减退症中的孤立性黄韧带骨化

Isolated ligamentum flavum ossification in primary hypoparathyroidism.

作者信息

Sohail Amir H, Maan Muhammad A A, Khan Muhammad S, Masood Qamar

机构信息

Aga Khan University Medical College, Karachi, Pakistan.

Department of Medicine, Aga Khan University, Karachi, Pakistan.

出版信息

Surg Neurol Int. 2018 Jan 10;9:4. doi: 10.4103/sni.sni_364_17. eCollection 2018.

Abstract

BACKGROUND

The ligamenta flava can undergo ossification and calcification resulting in myelopathy. Only seven cases of ligamentum flavum ossification in association with hypoparathyroidism have been reported, most of which had concurrent osseous changes in other spinal ligaments. Here, we report a patient with hypoparathyroidism who presented with ligamentum flavum ossification causing both cervical and thoracic myelopathy.

CASE DESCRIPTION

A 43-year-old male presented with backache, urinary retention, and lower limb weakness for the last few days. Magnetic resonance imaging scan showed ossification of the ligamentum flavum in the cervical and thoracic regions, with severe spinal stenosis. Following spinal decompressive surgery, the patient made a complete recovery. Primary hypoparathyroidism was found to be the underlying cause for ligamentum flavum ossification.

CONCLUSION

Ossification of ligamentum flavum secondary to hypoparathyroidism should be considered as a possible cause of myelopathy in all patients presenting with symptoms of spinal cord compression.

摘要

背景

黄韧带可发生骨化和钙化,导致脊髓病。仅有7例黄韧带骨化合并甲状旁腺功能减退的病例报道,其中大多数患者其他脊柱韧带同时存在骨质改变。在此,我们报告1例甲状旁腺功能减退患者,其因黄韧带骨化导致颈段和胸段脊髓病。

病例描述

一名43岁男性,在过去几天出现背痛、尿潴留和下肢无力。磁共振成像扫描显示颈段和胸段黄韧带骨化,伴有严重的椎管狭窄。经过脊柱减压手术后,患者完全康复。原发性甲状旁腺功能减退被发现是黄韧带骨化的潜在原因。

结论

对于所有出现脊髓受压症状的患者,甲状旁腺功能减退继发的黄韧带骨化应被视为脊髓病的可能病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a611/5778726/604cc6dcfb82/SNI-9-4-g002.jpg

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