体内宽带可见光光学相干断层扫描探头可实现反向光谱分析。
In vivo broadband visible light optical coherence tomography probe enables inverse spectroscopic analysis.
作者信息
Winkelmann James A, Eid Aya, Nguyen The-Quyen, Bui Thang, Yi Ji, Backman Vadim
出版信息
Opt Lett. 2018 Feb 1;43(3):619-622. doi: 10.1364/OL.43.000619.
Abstract
We report the design and characterization of a 6 mm outer diameter pull-back circumferential scanning visible optical coherence tomography probe. The probe's large visible bandwidth (500-695 nm) allowed for inverse spectroscopic analysis and an axial resolution of ∼1.1 μm in tissue. We verify spectral imaging capabilities by measuring microsphere backscattering spectra and demonstrate in vivo spatial nanoscale characterization of tissue.
摘要
我们报告了一种外径为6毫米的回撤式圆周扫描可见光学相干断层扫描探头的设计与特性。该探头具有较大的可见带宽（500 - 695纳米），可用于逆光谱分析，在组织中的轴向分辨率约为1.1微米。我们通过测量微球背散射光谱验证了光谱成像能力，并展示了组织的体内空间纳米级特征。
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