Department Occupational Medicine and Epidemiology, National Institute of Occupational Health, Box 8149 Deptartment, 0033 Oslo, Norway.
Department for Work Psychology and Physiology, National Institute of Occupational Health, Box 8149 0033 Oslo, Norway.
Int J Environ Res Public Health. 2018 Feb 4;15(2):264. doi: 10.3390/ijerph15020264.
In line with recommendations from both the World Health Organization and the European Union some employers encourage workplace health promotion through physical activity (PA) facilities and leisure time PA-initiatives. The current study describes a 15-month follow-up after an 8-week workplace delivered PA-initiative, investigates if improvements in cardiovascular risk status are sustainable, and elucidates differences according to educational level. One hundred and twenty one employees (43 women) were examined before and after the 8-week PA-initiative and 94 at the 15-month follow-up. PA-levels, blood pressure, resting heart rate, lipids, glycosylated hemoglobin (HbA1c), C-reactive protein (CRP), and selected markers of inflammation were registered at baseline, immediately after the 8-week PA-initiative, and 15 months after baseline. At the end of follow-up (15-month), PA-levels-increased during the 8-week intervention-had returned to baseline values. None of the five improvements in cardiovascular markers (total cholesterol, low density lipoprotein (LDL), P-selectin, CD40Ligand (CD40L) and Monocyte chemoattractant protein-1 (MCP-1)) seen at the 8-week follow-up were sustained. At the 15-month follow-up as compared to baseline HbA1c, CRP (log) and interleukin-6 (IL-6) were reduced by 0.06 mmol/L (95% CI -0.11,-0.01), 0.25 mg/L (95% CI -0.46,-0.04) and 0.39 pg/mL (95% CI -0.75, -0.04), respectively. At baseline, there were differences in cardiovascular risk factors comparing men with low versus high levels of education. No differences in changes in outcomes between these groups of men were found during follow-up. In this study highly educated men generally have lower levels of cardiovascular risk factors, but the effect of PA on such markers in this group do not differ from the effects seen in less educated men.
根据世界卫生组织和欧盟的建议，一些雇主通过提供体育锻炼设施和休闲时间体育锻炼计划来鼓励工作场所的健康促进。本研究描述了一项为期 8 周的工作场所体育锻炼计划后的 15 个月随访结果，旨在调查心血管风险状况的改善是否可持续，并根据教育水平阐明差异。121 名员工（43 名女性）在 8 周体育锻炼计划前后以及 94 名员工在 15 个月随访时接受了检查。在基线、8 周体育锻炼计划结束时以及 15 个月随访时，记录了体育锻炼水平、血压、静息心率、血脂、糖化血红蛋白（HbA1c）、C 反应蛋白（CRP）以及炎症的一些标志物。在随访结束时（15 个月），8 周干预期间增加的体育锻炼水平已恢复到基线值。在 8 周随访时观察到的五项心血管标志物（总胆固醇、低密度脂蛋白（LDL）、P-选择素、CD40Ligand（CD40L）和单核细胞趋化蛋白-1（MCP-1））的改善均未持续。与基线相比，在 15 个月随访时，HbA1c、CRP（对数）和白细胞介素-6（IL-6）分别降低了 0.06mmol/L（95%CI-0.11，-0.01）、0.25mg/L（95%CI-0.46，-0.04）和 0.39pg/mL（95%CI-0.75，-0.04）。在基线时，比较低教育水平与高教育水平的男性，心血管危险因素存在差异。在随访期间，未发现这些男性组之间的结果变化存在差异。在这项研究中，受教育程度较高的男性通常具有较低的心血管危险因素水平，但体育锻炼对该组标志物的影响与受教育程度较低的男性没有区别。
