Ge Hongli, Turhong Muhetar, Abudkrem Munire, Tang Yuhai
Xi'an Jiaotong University, Xi'an 710061, China.
Kashi Teachers' College, Kashi 844006, China.
J Pharm Anal. 2013 Aug;3(4):278-284. doi: 10.1016/j.jpha.2012.12.004. Epub 2013 Jan 29.
In many areas of China s used as . Although the two herbs have similar appearance and many similar compounds, they are totally different medicinal material, and have different pharmacodynamic actions. The fingerprint spectrum can be a good tool to distinguish the two herbs and control the quality of . In this paper, the chemical fingerprint of was established using raw materials from 15 origins in China. The chromatographic separations were obtained by a SHIM-PACK VP-ODS column (150 mm×4.6 mm i.d., 5 μm) using gradient elution, and run time of 80 min. The peak of linarin was considered as the control peak. The experimental data were analyzed with the software of Similarity Evaluation System for Chromatographic Fingerprint of Traditional Chinese Medicine (Version 2004A) and the quality control system of both the overall qualitative similarities and the overall quantitative similarities of traditional Chinese medicine chromatographic fingerprints.
在中国许多地区，[具体草药名称1]被用作[用途]。虽然这两种草药外观相似且含有许多相似的化合物，但它们是完全不同的药材，具有不同的药效作用。指纹图谱可以成为区分这两种草药并控制[具体草药名称1]质量的良好工具。本文利用来自中国15个产地的原材料建立了[具体草药名称1]的化学指纹图谱。采用SHIM-PACK VP-ODS柱（150 mm×4.6 mm内径，5μm）进行梯度洗脱，得到色谱分离结果，运行时间为80分钟。将蒙花苷峰作为对照峰。实验数据采用《中药色谱指纹图谱相似度评价系统》（2004A版）软件以及中药色谱指纹图谱整体定性相似度和整体定量相似度的质量控制系统进行分析。
