Kanakapura Basavaiah, Penmatsa Vamsi Krishna
Department of Chemistry, University of Mysore, Manasagangotri, Mysore 570006, Karnataka, India.
J Pharm Anal. 2016 Jun;6(3):137-149. doi: 10.1016/j.jpha.2016.01.003. Epub 2016 Jan 25.
Terbinafine is a new powerful antifungal agent indicated for both oral and topical treatment of mycosessince. It is highly effective in the treatment of determatomycoses. The chemical and pharmaceutical analysis of the drug requires effective analytical methods for quality control and pharmacodynamic and pharmacokinetic studies. Ever since it was introduced as an effective antifungal agent, many methods have been developed and validated for its assay in pharmaceuticals and biological materials. This article reviews the various methods reported during the last 25 years.
特比萘芬是一种新型强效抗真菌药，适用于口服和局部治疗真菌感染。它在治疗皮肤真菌病方面非常有效。该药物的化学和药物分析需要有效的分析方法用于质量控制以及药效学和药代动力学研究。自从它作为一种有效的抗真菌药被引入以来，已经开发并验证了许多用于其在药物和生物材料中测定的方法。本文综述了过去25年中报道的各种方法。
