Ohle Robert, Anjum Omar, Bleeker Helena, Wells George, Perry Jeffrey J
Department of Emergency Medicine, The Ottawa Hospital Research Institute, University of Ottawa, 1053 Carling Avenue, Room F662, Ottawa, Ontario, K1Y 4E9, Canada.
Department of Undergraduate Medicine, University of Ottawa, Ottawa, Canada.
Emerg Radiol. 2018 Jun;25(3):293-298. doi: 10.1007/s10140-018-1587-x. Epub 2018 Feb 5.
Acute aortic dissection (AAD) is a life-threatening condition making early diagnosis critical. Although 90% present with acute pain, the myriad of associated symptoms can make diagnosis a challenge. Our objective was to assess how we are using computed tomography to rule out acute aortic dissection specifically rate of ordering, diagnostic yield, and variation in practice.
We included consecutive adult patients presenting to two tertiary academic care emergency departments over one calendar year presenting with non-traumatic chest, back, abdominal, or flank pain. Primary outcome was rate of CT thorax/abdomen ordered to rule out AAD. Secondary outcome was variation in CT ordering, measured comparing number of CTs ordered per physician. Sample size of 12 per group was calculated based on an expected delta in mean CT ordered of 5 and a within group SD of 3.
Thirty-one thousand two hundred one patients presented with truncal pain during the study period, 22,729 were included (mean 47 years, SD 18.5 years, 56.2% female); prevalence of AAD (N = 4) was 0.02%. CT was ordered to rule out AAD in 175 (0.7%) patients (mean 62 years, SD 16.5, 50.6% female). Significant variation between physicians ordering was found, with individual physicians ordering varying from 0.6 to 12%.
Current rate of imaging for acute aortic dissection is low and potentially inefficient, with a large variation in practice. These findings suggest potential for more standardized and efficient use of CT for the diagnosis of acute aortic dissection.
急性主动脉夹层(AAD)是一种危及生命的疾病,早期诊断至关重要。尽管90%的患者表现为急性疼痛,但众多相关症状会使诊断成为一项挑战。我们的目的是评估我们如何使用计算机断层扫描来排除急性主动脉夹层,具体包括检查开单率、诊断率以及实践中的差异。
我们纳入了在一个日历年度内连续就诊于两家三级学术医疗急诊科的成年患者,这些患者出现非创伤性胸痛、背痛、腹痛或胁腹痛。主要结局是为排除AAD而开具胸部/腹部CT检查的比率。次要结局是CT检查开单的差异,通过比较每位医生开具的CT检查数量来衡量。根据预期的平均CT检查数量差异为5以及组内标准差为3,计算出每组12例的样本量。
在研究期间,有31201例患者出现躯干疼痛,其中22729例被纳入研究(平均年龄47岁,标准差18.5岁,女性占56.2%);AAD的患病率(N = 4)为0.02%。175例(0.7%)患者开具了CT检查以排除AAD(平均年龄62岁,标准差16.5,女性占50.6%)。发现医生之间的开单存在显著差异,个别医生的开单率从0.6%到12%不等。
目前急性主动脉夹层的影像学检查率较低且可能效率不高,实践中存在很大差异。这些发现表明在急性主动脉夹层诊断中更标准化、高效地使用CT具有潜力。