D'Ambrosi Riccardo, Maccario Camilla, Serra Nicola, Ursino Chiara, Usuelli Federico Giuseppe
Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Milan, Italy; IRCCS Istituto Ortopedico Galeazzi, U.O. CASCO - Piede e Caviglia, Milan, Italy.
Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Milan, Italy; IRCCS Istituto Ortopedico Galeazzi, U.O. CASCO - Piede e Caviglia, Milan, Italy.
Foot Ankle Surg. 2018 Aug;24(4):365-372. doi: 10.1016/j.fas.2017.04.011. Epub 2017 Apr 23.
The aim of the study was to assess the relationship between symptomatic osteochondral lesions of the talus (OLTs) and age, body mass index (BMI), quality of life (QOL), size and anatomic location.
Fifty-two patients with chronic OLTs were analyzed including BMI, Visual Analogue Scale (VAS), American Orthopaedic Foot and Ankle Society (AOFAS), Short-Form Health Survey (SF-12 divided into Mental (MCS) and Physical (PCS) score) and the 12-Item General Health Questionnaire (GHQ-12). Every patient underwent magnetic resonance imaging (MRI) and computed tomography (CT) examinations. We carried out a sub-analysis by dividing the talus into 6 areas, 3 vertical (medial, central and lateral group) and 3 horizontal (anterior, middle and posterior group).
There were 31 (60%) male and 21 (40%) female patients. Mean MCS and PCS resulted respectively 43.9 and 35.2. OLTs were located as follows: medial 20 (38.50%); central 13 (24.0%); and lateral 19 (36.50%); anterior 24 (46.15%); middle 16 (30.77%); and posterior 12 (23.08%). No significant differences were found among different groups with the exception of the anterior and posterior group for MCS (p=0.021). In the central group we identified a negative correlation (R=-0.672) between aging and AOFAS and a positive correlation between BMI and lesion size. We found a positive correlation between CT and MRI in each group.
OLTs impact patients' quality of life particularly in the physical component. Additionally, in patients with central lesions we found a positive linear correlation between lesion size and BMI and a worsening of the ankle with increasing age.
本研究的目的是评估距骨有症状的骨软骨损伤（OLTs）与年龄、体重指数（BMI）、生活质量（QOL）、大小及解剖位置之间的关系。
对52例慢性OLTs患者进行分析，内容包括BMI、视觉模拟量表（VAS）、美国矫形足踝协会（AOFAS）评分、简短健康调查问卷（SF-12分为精神健康评分（MCS）和身体健康评分（PCS））以及12项一般健康问卷（GHQ-12）。每位患者均接受了磁共振成像（MRI）和计算机断层扫描（CT）检查。我们将距骨分为6个区域进行亚分析，3个垂直区域（内侧、中央和外侧组）和3个水平区域（前侧、中间和后侧组）。
有31例（60%）男性和21例（40%）女性患者。平均MCS和PCS分别为43.9和35.2。OLTs的位置分布如下：内侧20例（38.50%）；中央13例（24.0%）；外侧19例（36.50%）；前侧24例（46.15%）；中间16例（30.77%）；后侧12例（23.08%）。除了前侧和后侧组的MCS有显著差异（p = 0.021）外，不同组之间未发现显著差异。在中央组中，我们发现年龄与AOFAS之间呈负相关（R = -0.672），BMI与损伤大小之间呈正相关。我们发现每组中CT和MRI之间呈正相关。
OLTs会影响患者的生活质量，尤其是在身体方面。此外，在中央损伤的患者中，我们发现损伤大小与BMI之间呈正线性相关，且随着年龄增长踝关节功能恶化。
