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青少年怀孕的不良围产期结局:匈牙利东南部5年期间的分析

Adverse perinatal outcome in teenage pregnancies: an analysis of a 5-year period in Southeastern Hungary.

作者信息

Karai Adrienn, Gyurkovits Zita, Nyári Tibor András, Sári Tamás, Németh Gábor, Orvos Hajnalka

机构信息

a Department of Pediatrics , University of Szeged , Szeged , Hungary.

b Department of Obstetrics and Gynecology , University of Szeged , Szeged , Hungary.

出版信息

J Matern Fetal Neonatal Med. 2019 Jul;32(14):2376-2379. doi: 10.1080/14767058.2018.1438393. Epub 2018 Feb 19.

DOI:10.1080/14767058.2018.1438393
PMID:29409369
Abstract

OBJECTIVE

To determine the risks of adverse perinatal outcomes of teenage mothers.

MATERIAL AND METHODS

A retrospective analysis was performed on teenage mothers (under 20 years of age) who delivered in the period of 2010-2014 at the Department of Obstetrics and Gynecology, University of Szeged (study group). All mothers who delivered in Hungary during the same period were studied as a control group. The following parameters were analyzed: demographic data of the mothers, maternal complications, perinatal outcome and congenital malformations of the newborns. The binominal test, Student's t-test and Poisson's regression were applied using STATA 9.0 (StataCorp, College Station, TX, USA) statistical software (p < .05 was considered to be statistically significant).

RESULTS

During this 5-year period, 12,845 births were recorded at the Department, of these 274 (2.1%) were teenage pregnancies with 275 newborns. The offsprings of teenage mothers had significantly lower mean birth weight (3110.2 ± 564.03 g versus 3247 g), higher rate of congenital malformations (8.0 versus 5.0%) and higher admission to neonatal intensive care unit (12.4 versus 8.0%) than the infants in the control group.

CONCLUSIONS

Younger maternal age was significantly associated with lower mean birth weight, higher risk of congenital malformations, and increased admission rate to neonatal intensive care unit.

摘要

目的

确定青少年母亲围产期不良结局的风险。

材料与方法

对2010 - 2014年期间在塞格德大学妇产科分娩的青少年母亲(20岁以下)进行回顾性分析(研究组)。将同期在匈牙利分娩的所有母亲作为对照组进行研究。分析了以下参数:母亲的人口统计学数据、母亲并发症、围产期结局以及新生儿的先天性畸形。使用STATA 9.0(美国德克萨斯州大学站市StataCorp公司)统计软件进行二项式检验、学生t检验和泊松回归分析(p < 0.05被认为具有统计学意义)。

结果

在这5年期间,该科室记录了12,845例分娩,其中274例(2.1%)为青少年妊娠,产下275名新生儿。与对照组婴儿相比,青少年母亲的后代平均出生体重显著更低(3110.2 ± 564.03克对3247克),先天性畸形发生率更高(8.0%对5.0%),入住新生儿重症监护病房的比例更高(12.4%对8.0%)。

结论

母亲年龄较小与平均出生体重较低、先天性畸形风险较高以及入住新生儿重症监护病房的比例增加显著相关。

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