Department of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, KY 40536, USA.
Department of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, KY 40536, USA.
Microbes Infect. 2018 Aug-Sep;20(7-8):445-450. doi: 10.1016/j.micinf.2018.01.002. Epub 2018 Feb 2.
The intonation "The king is dead, long live the king" aptly describes the state of Chlamydia research. Genetic-based approaches are rapidly replacing correlative strategies to provide new insights. We describe how current transformation technologies are enhancing progress in understanding Chlamydia infection biology and present key opportunities for further development.
“国王死了,国王万岁”这个成语恰当地描述了衣原体研究的现状。基于遗传学的方法正在迅速取代相关性策略,为人们提供新的见解。我们描述了当前的转化技术如何增强人们对衣原体感染生物学的理解,并提出了进一步发展的关键机会。