a Microbiology and Diagnostics , Bruker Daltonik GmbH , Bremen , Germany.
Expert Rev Proteomics. 2018 Mar;15(3):193-202. doi: 10.1080/14789450.2018.1438193. Epub 2018 Feb 13.
The introduction of the MALDI Biotyper in laboratories substantially changed microbiology practice, this has been called a revolution. The system accelerated diagnostic while costs were reduced and accuracy was increased. In just a few years MALDI-TOF MS became the first-line identification tool for microorganisms. Ten years after its introduction, more than 2000 MALDI Biotyper systems are installed in laboratories which are performing routine diagnostic, and the number is still increasing. Areas covered: This article summarises changes in clinical microbiology introduced by the MALDI Biotyper and its effects, as it has been published in peer reviewed articles found in PubMed. Further, the potential of novel developments to increase the value of the system is described. Expert commentary: The MALDI Biotyper has significantly improved clinical microbiology in the area of microorganism identification. Now new developments and applications, e.g. for typing and resistance testing, might further increase its value in clinical microbiology. The systems might get the central diagnostic analyser which is getting integrated into the widely automated microbiology laboratories of the future.
MALDI Biotyper 在实验室中的引入极大地改变了微生物学的实践，这被称为一场革命。该系统加速了诊断，同时降低了成本并提高了准确性。在短短几年内，MALDI-TOF MS 成为了微生物的一线鉴定工具。在其推出十年后，已有 2000 多个 MALDI Biotyper 系统安装在进行常规诊断的实验室中，而且这个数字还在不断增加。涵盖领域：本文总结了 MALDI Biotyper 引入的临床微生物学的变化及其影响，这些内容均发表在 PubMed 中的同行评审文章中。此外，还描述了新的发展可能增加该系统价值的潜力。专家评论：MALDI Biotyper 极大地改善了微生物鉴定领域的临床微生物学。现在，新的发展和应用，例如分型和耐药性测试，可能会进一步提高其在临床微生物学中的价值。该系统可能会成为集成到未来广泛自动化的微生物学实验室中的中央诊断分析仪。
