Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università degli Studi di Messina, viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Food Chem. 2018 Jun 1;250:155-161. doi: 10.1016/j.foodchem.2017.12.091. Epub 2018 Jan 2.
A Headspace-Solid Phase Microextraction-Gas Chromatography-Mass Spectrometry (HS-SPME-GC-MS) method was developed and validated for the simultaneous determination of furan, 2-methylfuran, 2-ethylfuran, 2-butylfuran, 2-pentylfuran, 2-acetylfuran, furfural and furfuryl alcohol in jarred baby food. The method was specific for the analytes. Good precision was obtained both in terms of intra-day repeatability (RSD ≤ 5.02) and inter-day precision (RSD ≤ 5.55%). The recovery values were between 98.42% and 99.8%. Linearity was established over two order of magnitude, and the achieved LODs and LOQs ranged between 0.018 and 0.035 ng/g and 0.060-0.117 ng/g, respectively, depending on the analyte. Finally, the method was successfully applied to investigate the content of furan and furan derivatives in several commercial baby food samples containing fruit or meat. The results showed that this simple, rapid and solvent free procedure could be used routinely for the analysis of baby food providing competent quantitative data functional to risk assessment.
建立并验证了一种同时测定罐装婴儿食品中糠醛、2-甲基糠醛、2-乙基糠醛、2-丁基糠醛、2-戊基糠醛、2-乙酰基糠醛、糠酸和糠醇的顶空固相微萃取-气相色谱-质谱法（HS-SPME-GC-MS）。该方法对分析物具有特异性。日内重复性（RSD≤5.02）和日间精密度（RSD≤5.55%）均获得良好的精密度。回收率在 98.42%至 99.8%之间。线性范围为两个数量级，所得到的检测限和定量限范围分别为 0.018-0.035ng/g 和 0.060-0.117ng/g，具体取决于分析物。最后，该方法成功应用于检测几种含有水果或肉类的商业婴儿食品中呋喃和呋喃衍生物的含量。结果表明，该简单、快速、无溶剂的方法可常规用于婴儿食品的分析，为风险评估提供有价值的定量数据。
