School of Biosystems Engineering and Food Science, Zhejiang University , 866 Yuhangtang Road, Hangzhou 310058, P.R. China.
ACS Appl Mater Interfaces. 2017 Jul 19;9(28):23287-23301. doi: 10.1021/acsami.7b03937. Epub 2017 Jul 7.
Food chemical contaminants are a major factor in the cause of foodborne diseases and can do harm to human health. Hence, it is highly desirable to develop robust, easy, and sensitive methods for rapid evaluation of food chemical contaminants. Nanomaterial-based optical aptasensors combined with the advantages of the high selectivity of optical detection techniques, excellent stability of aptamer, and the unique properties of nanomaterials have been recognized as useful tools for routine biosensing applications. The recent progress in nanomaterial-based optical aptamer assays to determine food chemical contaminants including heavy metals, toxins, pesticides, and antibiotics are presented in this paper. Furthermore, the major challenges and future prospects in this field are discussed to provide ideas for further research.
食品化学污染物是食源性疾病的主要成因，会对人类健康造成危害。因此，开发用于快速评估食品化学污染物的强大、简便和灵敏的方法非常可取。基于纳米材料的光学适配体传感器结合了光学检测技术的高选择性、适配体的优异稳定性以及纳米材料的独特性质的优势，已被认为是常规生物传感应用的有用工具。本文介绍了基于纳米材料的光学适配体测定法在测定食品化学污染物（包括重金属、毒素、农药和抗生素）方面的最新进展。此外，还讨论了该领域面临的主要挑战和未来展望，为进一步研究提供思路。
