Department of Chemical Sciences, Fountain University Osogbo, Nigeria.
Biosens Bioelectron. 2018 May 30;106:149-178. doi: 10.1016/j.bios.2018.01.030. Epub 2018 Jan 31.
This review discusses recent graphene (GR) electrochemical biosensor for accurate detection of biomolecules, including glucose, hydrogen peroxide, dopamine, ascorbic acid, uric acid, nicotinamide adenine dinucleotide, DNA, metals and immunosensor through effective immobilization of enzymes, including glucose oxidase, horseradish peroxidase, and haemoglobin. GR-based biosensors exhibited remarkable performance with high sensitivities, wide linear detection ranges, low detection limits, and long-term stabilities. Future challenges for the field include miniaturising biosensors and simplifying mass production are discussed.
这篇综述讨论了最近的石墨烯（GR）电化学生物传感器，用于准确检测生物分子，包括葡萄糖、过氧化氢、多巴胺、抗坏血酸、尿酸、烟酰胺腺嘌呤二核苷酸、DNA、金属和免疫传感器，通过有效固定酶，包括葡萄糖氧化酶、辣根过氧化物酶和血红蛋白。基于 GR 的生物传感器表现出出色的性能，具有高灵敏度、宽线性检测范围、低检测限和长期稳定性。该领域未来的挑战包括生物传感器的小型化和简化大规模生产。
