Farooqi Ashar M, Padilla Jennifer M, Monteith Teshamae S
Department of Neurology-Headache Division, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
Brain Sci. 2018 Feb 7;8(2):29. doi: 10.3390/brainsci8020029.
The goal of this review is to explore the literature reports of acute confusional migraine (ACM) including patient characteristics, migraine symptomatology, and proposed diagnostic criteria. A literature review was conducted using PubMed, Scopus and Web of Science using the terms "confusional migraine" and "confusional state in migraine". All the relevant articles from 1970 to 2016 were included. A total of 120 patients were found in the literature. Most of the cases were seen in the pediatric population with a slight male predominance. Personal or family history of migraine was common. Most patients had a headache prior to the confusional state. In addition to confusion and agitation, some developed visual (32.5%) and/or sensory symptoms (19%) and/or speech problems (39%) either prior to or during the confusional state. Data on treatment outcomes is lacking. Patients with most common forms of migraine report attention and cognitive disturbances but awareness remains intact as opposed to patients with ACM. ACM is a distinct entity and should be included as part of the appendix of International Classification of Headache Disoders-3 beta version (ICHD-3β) criteria. Prospective studies are needed to further study this disorder and its association with other migraine forms.
本综述的目的是探讨急性混乱性偏头痛（ACM）的文献报道，包括患者特征、偏头痛症状学及拟议的诊断标准。使用PubMed、Scopus和Web of Science数据库，以“混乱性偏头痛”和“偏头痛中的混乱状态”为检索词进行文献综述。纳入了1970年至2016年期间所有相关文章。文献中总共发现了120例患者。大多数病例见于儿童人群，男性略占优势。偏头痛的个人史或家族史很常见。大多数患者在出现混乱状态之前有头痛症状。除了混乱和激越外，一些患者在混乱状态之前或期间还出现视觉症状（32.5%）和/或感觉症状（19%）和/或言语问题（39%）。缺乏关于治疗结果的数据。大多数常见偏头痛形式的患者会出现注意力和认知障碍，但与ACM患者不同，其意识仍保持完整。ACM是一种独特的疾病实体，应纳入《国际头痛疾病分类第3版β版》（ICHD-3β）标准的附录中。需要进行前瞻性研究以进一步研究这种疾病及其与其他偏头痛形式的关联。
