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《御用药用噬菌体》

The Magistral Phage.

机构信息

Laboratory for Molecular and Cellular Technology, Queen Astrid Military Hospital, Bruynstraat 1, 1120 Brussel, Belgium.

Bacterial Diseases, Unit Antibiotic Resistance, Scientific Institute of Public Health, Rue Engelandstraat 642, 1180 Brussel, Belgium.

出版信息

Viruses. 2018 Feb 6;10(2):64. doi: 10.3390/v10020064.

Abstract

Since time immemorial, phages-the viral parasites of bacteria-have been protecting Earth's biosphere against bacterial overgrowth. Today, phages could help address the antibiotic resistance crisis that affects all of society. The greatest hurdle to the introduction of phage therapy in Western medicine is the lack of an appropriate legal and regulatory framework. Belgium is now implementing a pragmatic phage therapy framework that centers on the magistral preparation (compounding pharmacy in the US) of tailor-made phage medicines.

摘要

自古以来,噬菌体——细菌的病毒寄生虫——一直在保护地球生物圈免受细菌过度生长的影响。如今,噬菌体可能有助于解决影响整个社会的抗生素耐药性危机。噬菌体疗法在西方医学中引入的最大障碍是缺乏适当的法律和监管框架。比利时现在正在实施一个实用的噬菌体治疗框架,该框架以定制噬菌体药物的大师级制备(美国的调配药房)为中心。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1991/5850371/c992a97af217/viruses-10-00064-g001.jpg

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