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1
High diabetes prevalence among tuberculosis cases in Kerala, India.印度喀拉拉邦结核病患者中糖尿病患病率较高。
PLoS One. 2012;7(10):e46502. doi: 10.1371/journal.pone.0046502. Epub 2012 Oct 15.
2
Factors associated with delayed diagnosis of pulmonary tuberculosis in the state of Rio de Janeiro, Brazil.与巴西里约热内卢州肺结核延迟诊断相关的因素。
J Bras Pneumol. 2011 Jul-Aug;37(4):512-20. doi: 10.1590/s1806-37132011000400014.
3
The delay in diagnosis of tuberculosis in the Monteregie region of Quebec, Canada.加拿大魁北克省蒙特利尔地区结核病诊断的延迟情况。
Mcgill J Med. 2008 Jul;11(2):124-31.
4
Gender and socio-cultural determinants of delay to diagnosis of TB in Bangladesh, India and Malawi.孟加拉国、印度和马拉维结核病诊断延迟的性别及社会文化决定因素
Int J Tuberc Lung Dis. 2008 Jul;12(7):848-55.
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Predictors of treatment delays for tuberculosis in Sikkim.锡金邦结核病治疗延迟的预测因素。
Natl Med J India. 2006 Mar-Apr;19(2):60-3.
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Characteristics of patients with delayed diagnosis of infectious pulmonary tuberculosis.传染性肺结核延迟诊断患者的特征。
Respirology. 2005 Mar;10(2):196-200. doi: 10.1111/j.1440-1843.2005.00644.x.
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Patterns of delays amongst pulmonary tuberculosis patients in Lagos, Nigeria.尼日利亚拉各斯肺结核患者的延误模式。
BMC Public Health. 2004 May 29;4:18. doi: 10.1186/1471-2458-4-18.
8
Gender disparities in tuberculosis: report from a rural DOTS programme in south India.印度南部农村直接督导下的短程化疗项目中结核病的性别差异报告。
Int J Tuberc Lung Dis. 2004 Mar;8(3):323-32.
9
Why do patients with a cough delay seeking care at Lusaka urban health centres? A health systems research approach.为何咳嗽患者会延迟在卢萨卡城市医疗中心就医?一种卫生系统研究方法。
Int J Tuberc Lung Dis. 2002 Sep;6(9):796-805.
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Factors associated with patient and health system delays in the diagnosis of tuberculosis in South India.印度南部结核病诊断中与患者及卫生系统延误相关的因素
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喀拉拉邦肺结核患者的诊断延误及相关因素

Diagnostic delay and associated factors among patients with pulmonary tuberculosis in Kerala.

作者信息

Paramasivam Selvam, Thomas Bina, Chandran Priya, Thayyil Jayakrishnan, George Biju, Sivakumar C P

机构信息

Department of Community Medicine, K.A.P.Viswanatham Government Medical College, Tiruchirappalli, Tamil Nadu, India.

Department of Community Medicine, Government Medical College, Kozhikode, Kerala, India.

出版信息

J Family Med Prim Care. 2017 Jul-Sep;6(3):643-648. doi: 10.4103/2249-4863.222052.

DOI:10.4103/2249-4863.222052
PMID:29417023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5787970/
Abstract

INTRODUCTION

Delay in the diagnosis of tuberculosis (TB) can lead to an increased infectivity period, delayed treatment, and increased severity of the disease. The objective of this study was to estimate the diagnostic delay and factors associated with the delay in diagnosis among the newly diagnosed smear-positive pulmonary TB patients in Kerala, India.

MATERIALS AND METHODS

A cross-sectional study was conducted among TB patients who were in the intensive phase of directly observed treatment short-course treatment in four randomly selected TB units in a district in Kerala during the years 2012-2013. Diagnostic delay was defined as the delay between the onset of symptoms and diagnosis. Data collection using a modified World Health Organization questionnaire was done by interviewing 302 participants.

RESULTS

Mean age of the participants was 48.6 ± 14.5 years. Males constituted 76.5% of the study population. The mean diagnostic delay was 43.5 ± 29.1 days (median: 37 days). The median patient and health system delays were 16 days and 15 days, respectively. Patient delay (55.6%) contributed more than health system delay (44.4%). Poor knowledge about TB, first consulting a private physician, and increased number of consultations were found to be significantly associated with diagnostic delay.

CONCLUSION

The diagnostic delay in tuberculosis reported in this study was lower than other studies in India but it needs further reduction. Both patients and health providers play a role in a delay in diagnosis, and poor knowledge about the disease among the patients was one of the main risk factors. Interventions to improve knowledge and awareness of the disease and to increase the suspicion of chest symptomatic by health-care providers in the private sector are vital to reduce diagnostic delay.

摘要

引言

结核病(TB)诊断延迟会导致传染期延长、治疗延误以及病情加重。本研究的目的是估计印度喀拉拉邦新诊断的涂片阳性肺结核患者的诊断延迟情况以及与诊断延迟相关的因素。

材料与方法

2012 - 2013年期间,在喀拉拉邦一个地区随机选取的四个结核病防治单位,对正在接受直接观察短程治疗强化期的结核病患者进行了一项横断面研究。诊断延迟定义为症状出现与诊断之间的延迟。通过访谈302名参与者,使用经修改的世界卫生组织问卷进行数据收集。

结果

参与者的平均年龄为48.6 ± 14.5岁。男性占研究人群的76.5%。平均诊断延迟为43.5 ± 29.1天(中位数:37天)。患者和卫生系统延迟的中位数分别为16天和15天。患者延迟(55.6%)比卫生系统延迟(44.4%)的影响更大。发现对结核病知识了解不足、首次咨询私人医生以及咨询次数增加与诊断延迟显著相关。

结论

本研究报告的结核病诊断延迟低于印度的其他研究,但仍需进一步缩短。患者和卫生服务提供者在诊断延迟中都起到了作用,患者对疾病知识了解不足是主要危险因素之一。改善对疾病的知识和认识以及提高私营部门医疗服务提供者对胸部症状的怀疑度的干预措施对于减少诊断延迟至关重要。