From the Department of Radiological and Medical Laboratory Sciences (T.K., H. Isoda), Nagoya University Graduate School of Medicine, Nagoya, Japan
Divisions of Radiological Technology (T.K.).
AJNR Am J Neuroradiol. 2018 Mar;39(3):488-493. doi: 10.3174/ajnr.A5533. Epub 2018 Feb 1.
Innovative techniques and device-related advances have improved the outcomes of neuroendovascular treatment. 3D imaging has previously used 2 × 2 binning, but 1 × 1 binning has recently been made available. The aim of this study was to evaluate the quantitative ability of conebeam CT for stent delineation and to investigate its effectiveness in the clinical environment.
Four acquisition groups of 3D MIP images acquired using conebeam CT with varying conditions (acquisition time, 10 or 20 seconds and binning, 1 × 1 or 2 × 2) were compared. Two methods of analysis were performed, a phantom study and an analysis of 28 randomly selected patients. The phantom study assessed the contrast-to-noise ratio and full width at half maximum values in conebeam CT images of intracranial stent struts. In the clinical subjects, we assessed contrast-to-noise ratio, full width at half maximum, and dose-area product.
In the phantom study, the contrast-to-noise ratio was not considerably different between 10- and 20-second acquisition times at equivalent binning settings. Additionally, the contrast-to-noise ratio at equivalent acquisition times did not differ considerably by binning setting. For the full width at half maximum results, equivalent acquisition times differed significantly by binning setting. In the clinical analyses, the 10-second/1 × 1 group (versus 20 second/2 × 2) showed a higher contrast-to-noise ratio ( < .05) and a dose-area product reduced by approximately 70% ( < .05), but the difference in full width at half maximum was not significant ( = .20).
For stent-assisted coil embolization, quantitative assessment of conebeam CT showed that 10 second/1 × 1 was equivalent to 20 second/2 × 2 for imaging deployed intracranial stents. Furthermore, the 10-second/1 × 1 settings resulted in a much smaller DAP.
创新技术和设备相关进展提高了神经血管内治疗的效果。3D 成像之前使用 2×2 binning,但最近提供了 1×1 binning。本研究旨在评估锥形束 CT 对支架描绘的定量能力,并研究其在临床环境中的有效性。
使用锥形束 CT 以不同条件(采集时间 10 秒或 20 秒和 binning 1×1 或 2×2)获取 4 组 3D MIP 图像,并进行比较。进行了两种分析方法,即体模研究和 28 例随机患者的分析。体模研究评估颅内支架支柱锥形束 CT 图像的对比噪声比和半高全宽值。在临床受试者中,我们评估了对比噪声比、半高全宽和剂量面积乘积。
在体模研究中,在等效 binning 设置下,10 秒和 20 秒采集时间之间的对比噪声比没有明显差异。此外,在等效采集时间下,binning 设置之间的对比噪声比没有明显差异。对于半高全宽结果,等效采集时间的 binning 设置差异显著。在临床分析中,10 秒/1×1 组(与 20 秒/2×2 组相比)表现出更高的对比噪声比(<0.05)和剂量面积乘积降低约 70%(<0.05),但半高全宽的差异无统计学意义(=0.20)。
对于支架辅助线圈栓塞,锥形束 CT 的定量评估表明,10 秒/1×1 与 20 秒/2×2 对成像部署的颅内支架等效。此外,10 秒/1×1 设置导致 DAP 显著减小。