Beijing National Laboratory of Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Org Biomol Chem. 2018 Feb 28;16(9):1448-1451. doi: 10.1039/c8ob00023a.
Highly efficient transfer hydrogenations of imines were realized with as low as 0.1 mol% of B(CF) by using Hantzsch esters as a hydrogen source, furnishing a variety of amines in 80-99% yields. For the asymmetric transfer hydrogenations, up to 38% ee was obtained with chiral diene-derived boron Lewis acids.
通过使用 Hantzsch 酯作为氢源，以低至 0.1mol%的 B(CF)实现了亚胺的高效转移氢化，以 80-99%的产率得到了各种胺。对于不对称转移氢化，手性二烯衍生的硼路易斯酸可获得高达 38%的对映体过量。
