词汇检索还是语义知识？哪一个导致轻度和中度阿尔茨海默病患者的命名错误？
Lexical Retrieval or Semantic Knowledge? Which One Causes Naming Errors in Patients with Mild and Moderate Alzheimer's Disease?
作者信息
Salehi Masoome, Reisi Mohsen, Ghasisin Leila
机构信息
Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Neurology, Amin Hospital, Isfahan, Iran.
出版信息
Dement Geriatr Cogn Dis Extra. 2017 Nov 30;7(3):419-429. doi: 10.1159/000484137. eCollection 2017 Sep-Dec.
Abstract
BACKGROUND
The purpose of the study was to analyze naming errors in patients with Alz-heimer's disease in comparison to healthy subjects and determine the underlying cause of naming errors in these patients.
METHOD
In this study, we included 35 healthy elderly subjects, 23 patients with mild Alzheimer's disease, and 23 with moderate Alzheimer's disease. Forty-five images were used to determine the type of naming errors, and to identify the underlying cause of errors, matching an image with a written word was used.
RESULTS
Patients with Alz-heimer's disease had more naming errors compared with the group of healthy elderly, and patients with moderate Alzheimer's disease showed a slower reaction in matching an image with a written word.
CONCLUSION
Anomia in the initial phase of Alzheimer's disease is due to problems in lexical retrieval; however, as the disease advances, in addition to lexical retrieval problems, conceptual knowledge causes naming problems.
摘要
背景
本研究的目的是分析阿尔茨海默病患者与健康受试者相比的命名错误情况，并确定这些患者命名错误的潜在原因。
方法
在本研究中，我们纳入了35名健康老年受试者、23名轻度阿尔茨海默病患者和23名中度阿尔茨海默病患者。使用45张图片来确定命名错误的类型，并通过将图片与书面文字匹配来识别错误的潜在原因。
结果
与健康老年组相比，阿尔茨海默病患者有更多的命名错误，且中度阿尔茨海默病患者在将图片与书面文字匹配时反应更慢。
结论
阿尔茨海默病初期的命名障碍是由于词汇检索问题；然而，随着疾病进展，除了词汇检索问题外，概念知识也会导致命名问题。
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本文引用的文献
1
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Clinics (Sao Paulo). 2015 Jun;70(6):423-8. doi: 10.6061/clinics/2015(06)07. Epub 2015 Jun 1.
2
A new set of 272 pictures for psycholinguistic studies: Persian norms for name agreement, image agreement, conceptual familiarity, visual complexity, and age of acquisition.一组新的 272 张用于心理语言学研究的图片：波斯语的名称一致性、图像一致性、概念熟悉度、视觉复杂性和习得年龄的规范。
Behav Res Methods. 2015 Dec;47(4):1148-1158. doi: 10.3758/s13428-014-0537-0.
3
The elderly population in iran: an ever growing concern in the health system.伊朗的老年人口：卫生系统中日益令人担忧的问题。
Iran J Psychiatry Behav Sci. 2012 Fall;6(2):1-6.
4
Confrontation naming errors in Alzheimer's disease.阿尔茨海默病中的对答命名错误。
Dement Geriatr Cogn Disord. 2014;37(1-2):86-94. doi: 10.1159/000354359. Epub 2013 Oct 3.
5
The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.阿尔茨海默病所致痴呆的诊断：美国国家老龄化研究所-阿尔茨海默病协会工作组关于阿尔茨海默病诊断指南的建议。
Alzheimers Dement. 2011 May;7(3):263-9. doi: 10.1016/j.jalz.2011.03.005. Epub 2011 Apr 21.
6
Anomia as a marker of distinct semantic memory impairments in Alzheimer's disease and semantic dementia.失名症作为阿尔茨海默病和语义性痴呆中明显语义记忆损伤的标志物。
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7
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8
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9
Semantic error patterns on the Boston Naming Test in normal aging, amnestic mild cognitive impairment, and mild Alzheimer's disease: is there semantic disruption?正常衰老、遗忘型轻度认知障碍和轻度阿尔茨海默病患者在波士顿命名测试中的语义错误模式：是否存在语义破坏？
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10
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Neuropsychology. 2004 Jul;18(3):526-36. doi: 10.1037/0894-4105.18.3.526.
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