阿月浑子叶精油的化学成分和自由基清除活性。

Chemical composition and radical scavenging activity of Amygdalus pedunculata Pall leaves' essential oil.

机构信息

Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an, Shaanxi 710127, China.

College of Chemistry and Chemical Engineering, Yan'an University, Yan'an 716000, Shaanxi, China.

出版信息

Food Chem Toxicol. 2018 Sep;119:368-374. doi: 10.1016/j.fct.2018.02.012. Epub 2018 Feb 9.

DOI:10.1016/j.fct.2018.02.012

PMID:29432838

Abstract

The main objective of the current study was to investigate the components and radical scavenging activity of essential oil from Amygdalus pedunculata Pall leaves (APEO) extracted by an ultrasound-assisted method. Thirty-eight chemical components were identified in APEO using gas chromatography-mass spectrometry (GC-MS). APEO primarily consisted of alcohols (36.82%), esters (28.81%), ketones (1.47%), alkanes (18.61%) and phenols (8.93%). The most abundant compound was n-hexanol (33.49%). The antioxidant activity of APEO was characterized for 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical, hydroxyl radical (OH·), hydrogen peroxide (HO), and superoxide anion radical (O·) scavenging and Fe reduction, and the IC values were 2.32, 2.65, 2.42, 5.24 and 4.19 mg/mL, respectively. The IC values for HO scavenging and Fe reduction of APEO were less than those of ascorbic acid (Vc; 3.15 and 5.13 mg/mL). The results showed that APEO has a high radical scavenging activity.

摘要

本研究的主要目的是研究超声辅助法提取扁桃叶挥发油（APEO）的成分和自由基清除活性。采用气相色谱-质谱联用（GC-MS）法鉴定了 APEO 中的 38 种化学成分。APEO 主要由醇类（36.82%）、酯类（28.81%）、酮类（1.47%）、烷烃类（18.61%）和酚类（8.93%）组成。含量最丰富的化合物是正己醇（33.49%）。APEO 的抗氧化活性特征为 2,2-二苯基-1-苦肼基（DPPH）自由基、羟基自由基（OH·）、过氧化氢（HO）和超氧阴离子自由基（O·）清除和 Fe 还原，IC 值分别为 2.32、2.65、2.42、5.24 和 4.19mg/mL。APEO 对 HO 清除和 Fe 还原的 IC 值均小于抗坏血酸（Vc；3.15 和 5.13mg/mL）。结果表明，APEO 具有较高的自由基清除活性。