Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College London, London, UK.
Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.
Thorax. 2018 Sep;73(9):877-879. doi: 10.1136/thoraxjnl-2017-210865. Epub 2018 Feb 3.
Risks for cardiovascular diseases (CVDs) other than myocardial infarction and stroke in the general COPD population are not well quantified. We used a matched cohort study design and Cox regression to estimate relative risks for 12 separate CVDs in a large population-based cohort of patients with COPD over a 12-year period. Associations between COPD and individual CVDs were heterogeneous, with the highest relative risks observed for heart failure and diseases of the arterial circulation (in excess of 2.5 for those aged 64-75 years). Relative risks declined with increasing age but for most CVD outcomes remained unchanged over the study period.
在普通 COPD 人群中，除心肌梗死和中风以外的心血管疾病（CVDs）的风险尚未得到充分量化。我们使用匹配队列研究设计和 Cox 回归分析，在一个超过 12 年的大型基于人群的 COPD 患者队列中，估计了 12 种不同 CVD 的相对风险。COPD 与个别 CVD 之间的相关性存在异质性，心力衰竭和动脉循环疾病的相对风险最高（对于 64-75 岁的人群，超过 2.5）。相对风险随年龄的增加而下降，但对于大多数 CVD 结局，在研究期间并未改变。
