Department of Otolaryngology-Head and Neck Surgery, Emory University, Atlanta, GA.
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD.
Int Forum Allergy Rhinol. 2018 Feb;8(2):85-107. doi: 10.1002/alr.22070.
The available allergic rhinitis (AR) literature continues to grow. Critical evaluation and understanding of this literature is important to appropriately utilize this knowledge in the care of AR patients. The International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR) has been produced as a multidisciplinary international effort. This Executive Summary highlights and summarizes the findings of the comprehensive ICAR:AR document.
The ICAR:AR document was produced using previously described methodology. Specific topics were developed relating to AR. Each topic was assigned a literature review, evidence-based review (EBR), or evidence-based review with recommendations (EBRR) format as dictated by available evidence and purpose within the ICAR:AR document. Following iterative reviews of each topic, the ICAR:AR document was synthesized and reviewed by all authors for consensus.
Over 100 individual topics related to AR diagnosis, pathophysiology, epidemiology, disease burden, risk factors, allergy testing modalities, treatment, and other conditions/comorbidities associated with AR were addressed in the comprehensive ICAR:AR document. Herein, the Executive Summary provides a synopsis of these findings.
In the ICAR:AR critical review of the literature, several strengths were identified. In addition, significant knowledge gaps exist in the AR literature where current practice is not based on the best quality evidence; these should be seen as opportunities for additional research. The ICAR:AR document evaluates the strengths and weaknesses of the AR literature. This Executive Summary condenses these findings into a short summary. The reader is also encouraged to consult the comprehensive ICAR:AR document for a thorough description of this work.
过敏性鼻炎（AR）相关文献不断增加。批判性评估和理解这些文献对于将其知识恰当地应用于 AR 患者的护理非常重要。国际过敏与鼻科学共识声明：过敏性鼻炎（ICAR:AR）是由多学科国际努力产生的。本执行摘要重点介绍并总结了全面的 ICAR:AR 文件的发现。
使用先前描述的方法编写了 ICAR:AR 文件。针对 AR 制定了特定主题。根据可用证据和 ICAR:AR 文件中的目的，为每个主题分配了文献综述、基于证据的综述 (EBR) 或基于证据的推荐综述 (EBRR) 格式。在对每个主题进行反复审查后，对 ICAR:AR 文件进行综合，并由所有作者进行共识审查。
全面的 ICAR:AR 文件中涉及了 100 多个与 AR 诊断、病理生理学、流行病学、疾病负担、危险因素、过敏测试方式、治疗以及与 AR 相关的其他病症/合并症相关的个别主题。在此，执行摘要提供了这些发现的概述。
在对 AR 文献的 ICAR:AR 批判性审查中，确定了几个优势。此外，AR 文献中存在重大知识空白，当前的实践并非基于最佳质量的证据；这应被视为进一步研究的机会。ICAR:AR 文件评估了 AR 文献的优缺点。本执行摘要将这些发现浓缩为简短的摘要。鼓励读者参考全面的 ICAR:AR 文件，以获取这项工作的详细描述。
