Amorim A R, Mendes G S, Pena G P A, Santos N
Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
Zoonoses Public Health. 2018 Aug;65(5):501-504. doi: 10.1111/zph.12455. Epub 2018 Feb 13.
Hepatitis E virus (HEV) is an emerging pathogen that can be transmitted through contaminated raw or undercooked meat derived from domestic pigs. HEV infections have been documented among pig herds, pig products and environmental samples raising concern about the spread of the virus. HEV genotypes 3 and 4 are considered zoonotic and have been linked to human cases. HEV was detected in 51 of 335 bile samples (15.2%) from healthy pigs in Minas Gerais, Brazil. Phylogenetic analysis of partial sequences from ORF1 and ORF2 regions yielded discordant results, assigning isolates to subtypes 3c and 3i, respectively, suggesting intragenotypic HEV recombination.
戊型肝炎病毒（HEV）是一种新出现的病原体，可通过受污染的家猪生肉或未煮熟的猪肉传播。猪群、猪产品和环境样本中均有戊型肝炎病毒感染的记录，这引发了人们对该病毒传播的担忧。戊型肝炎病毒3型和4型被认为是人畜共患病原体，并与人类病例有关。在巴西米纳斯吉拉斯州健康猪的335份胆汁样本中，有51份（15.2%）检测到了戊型肝炎病毒。对开放阅读框1（ORF1）和开放阅读框2（ORF2）区域的部分序列进行系统发育分析，结果不一致，分别将分离株归为3c和3i亚型，提示戊型肝炎病毒存在基因型内重组。
