Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Department of Cardiology, Peking University First Hospital, Beijing, China.
J Epidemiol Community Health. 2018 Jun;72(6):539-544. doi: 10.1136/jech-2017-209464. Epub 2018 Feb 15.
Short sleep duration is a risk factor of cardiovascular disorder; however, the association between short sleep duration and carotid atherosclerosis has not been completely characterised. The aim of this study is to investigate the association between short sleep duration and carotid atherosclerosis.
We used the cross-sectional data collected between May 2014 and July 2014, which were based on a cardiovascular disease cohort study including 3798 participants aged 40 years and older who are residents of Beijing, China. We used logistic regression models to examine the associations between sleep duration and carotid atherosclerosis.
After the adjustment of covariates, short sleep duration (less than 5 hours per night) was found to be associated with carotid atherosclerosis, and it also elevated the risk of, in both terms, the increment of prevalence (OR=1.31, P<0.05) and the quantity of carotid plaques (OR=1.28, P<0.05). When age was also taken into consideration, the largest association, in both terms of prevalence (OR=3.46, P<0.01) and the number of carotid plaques (OR=4.23, P<0.01), was found in subjects over the age of 60 with short sleep duration.
In conclusion, sleep duration less than 5 hours per night is associated with a higher risk of carotid atherosclerosis compared with subjects who sleeps for 5 or over 5 hours per night, and the association may be modified by age.
睡眠时长过短是心血管疾病的一个风险因素；然而，睡眠时长过短与颈动脉粥样硬化之间的关联尚未被完全阐明。本研究旨在探讨睡眠时长过短与颈动脉粥样硬化之间的关联。
我们使用了 2014 年 5 月至 7 月期间收集的横断面数据，这些数据基于一项心血管疾病队列研究，共纳入了 3798 名年龄在 40 岁及以上、居住在北京的居民。我们使用逻辑回归模型来检验睡眠时长与颈动脉粥样硬化之间的关联。
在调整了协变量后，我们发现睡眠时长过短（每晚少于 5 小时）与颈动脉粥样硬化有关，并且增加了颈动脉粥样硬化的发生率（OR=1.31，P<0.05）和斑块数量（OR=1.28，P<0.05）的风险。当考虑到年龄因素时，我们发现睡眠时长过短的 60 岁以上人群在发生率（OR=3.46，P<0.01）和颈动脉斑块数量（OR=4.23，P<0.01）方面的关联最大。
总之，与每晚睡眠 5 小时或以上的人群相比，每晚睡眠不足 5 小时与颈动脉粥样硬化的风险增加相关，这种关联可能受年龄的影响。
