Guo Na, Tong Tuantuan, Ren Ning, Tu Youying, Li Bo
Department of Tea Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Department of Tea Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Phytochemistry. 2018 May;149:42-55. doi: 10.1016/j.phytochem.2018.02.002. Epub 2018 Feb 17.
Camellia seeds have been traditionally used as oil raw materials in Asia, and are known for a wide spectrum of applications. Oleanane-type triterpene saponins are the major specialised metabolites in Camellia seeds, and more than seventy saponins have been isolated and characterized. These natural compounds have caught much attention due to their various biological and pharmacological activities, including modulation of gastrointestinal system, anti-cancer, anti-inflammation, anti-microorganism, antioxidation, neuroprotection, hypolipidemic effects, foaming and detergence, as well as helping the accumulation of pollutants by plants. These compounds have a promising application in medicine, agriculture, industry and environmental protection. The present paper summarized the information from current publications on Camellia seed saponins, with a focus on the advances made in chemical structures, determination methods, bioactivities and toxicity. We hope this article will stimulate further investigations on these compounds.
山茶籽在亚洲传统上一直被用作油脂原料，并且以其广泛的应用而闻名。齐墩果烷型三萜皂苷是山茶籽中的主要次生代谢产物，已分离并鉴定出七十多种皂苷。这些天然化合物因其多种生物学和药理活性而备受关注，包括对胃肠道系统的调节、抗癌、抗炎、抗微生物、抗氧化、神经保护、降血脂作用、发泡和去污能力，以及帮助植物积累污染物。这些化合物在医药、农业、工业和环境保护方面具有广阔的应用前景。本文总结了当前关于山茶籽皂苷的出版物中的信息，重点关注其化学结构、测定方法、生物活性和毒性方面取得的进展。我们希望本文能激发对这些化合物的进一步研究。
