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磁共振波谱、正电子发射断层扫描与放射基因组学——与胶质瘤的相关性

Magnetic Resonance Spectroscopy, Positron Emission Tomography and Radiogenomics-Relevance to Glioma.

作者信息

Chiang Gloria C, Kovanlikaya Ilhami, Choi Changho, Ramakrishna Rohan, Magge Rajiv, Shungu Dikoma C

机构信息

Department of Neuroradiology, Weill Cornell Medical College, New York, NY, United States.

Radiology, Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States.

出版信息

Front Neurol. 2018 Feb 5;9:33. doi: 10.3389/fneur.2018.00033. eCollection 2018.

Abstract

Advances in metabolic imaging techniques have allowed for more precise characterization of gliomas, particularly as it relates to tumor recurrence or pseudoprogression. Furthermore, the emerging field of radiogenomics where radiographic features are systemically correlated with molecular markers has the potential to achieve the holy grail of neuro-oncologic neuro-radiology, namely molecular diagnosis without requiring tissue specimens. In this section, we will review the utility of metabolic imaging and discuss the current state of the art related to the radiogenomics of glioblastoma.

摘要

代谢成像技术的进步使得对胶质瘤的特征描述更加精确,特别是在肿瘤复发或假性进展方面。此外,放射基因组学这一新兴领域将影像学特征与分子标志物进行系统关联,有潜力实现神经肿瘤神经放射学的圣杯,即无需组织标本即可进行分子诊断。在本节中,我们将回顾代谢成像的应用,并讨论与胶质母细胞瘤放射基因组学相关的当前技术水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/198b/5807339/fb522f3cb53f/fneur-09-00033-g001.jpg

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