University of Michigan.
J Res Adolesc. 2018 Mar;28(1):10-25. doi: 10.1111/jora.12366.
Networks are often implicated in theories of adolescent brain development, but they are not regularly examined in empirical studies. The aim of this article is to address this disconnect between theory and quantitative methodology, using the dual systems model of adolescent decision making as a prototype. After reviewing the key task-related connectivity methods that have been applied in the adolescent neuroimaging literature (seed-based correlations, psychophysiological interactions, and dynamic causal modeling), a novel connectivity method is introduced (extended unified structural equation modeling). The potential of this method for understanding adolescent brain development is showcased with a simulation study: It creates person-specific networks that have direct and time-lagged connections that can be modulated by behavior.
网络在青少年大脑发育理论中经常被提及，但在实证研究中却没有得到定期检验。本文旨在弥合理论与定量方法之间的脱节，以青少年决策的双重系统模型为原型。在回顾了在青少年神经影像学文献中应用的关键任务相关连接方法（基于种子的相关性、心理生理相互作用和动态因果建模）之后，引入了一种新的连接方法（扩展统一结构方程建模）。通过一项模拟研究展示了该方法在理解青少年大脑发育方面的潜力：它创建了具有直接和时滞连接的个体特定网络，这些连接可以通过行为进行调节。
