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分泌型细菌RNA:一条未被探索的途径。

Secreted bacterial RNA: an unexplored avenue.

作者信息

Ghosal Anubrata

机构信息

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

出版信息

FEMS Microbiol Lett. 2018 Apr 1;365(7). doi: 10.1093/femsle/fny036.

Abstract

Gradually, it is becoming clear that our well-being depends significantly on the contribution and composition of microorganisms that are associated with us. The majority of human-associated microorganisms are bacteria, which maintain their niche through interactions with the human host and neighboring microorganisms. Secretory products contribute largely to maintaining their position in a complex ecosystem. The role of bacterial-released secreted RNA (seRNA) is mostly unexplored, and the study on seRNA will open a new branch in science. There are observations that have demonstrated the functional potential of seRNA, but more investigations are required to cover the entire path from their origin to function.

摘要

逐渐地,有一点变得清晰起来,即我们的健康很大程度上取决于与我们相关联的微生物的贡献和组成。大多数与人类相关的微生物是细菌,它们通过与人类宿主及邻近微生物的相互作用来维持其生态位。分泌产物在很大程度上有助于它们在复杂生态系统中维持自身地位。细菌释放的分泌RNA(seRNA)的作用大多尚未被探索,对seRNA的研究将开启科学的一个新分支。有观察结果表明了seRNA的功能潜力,但还需要更多研究来涵盖从其起源到功能的整个过程。

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