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65岁及以下或65岁以上患者退行性腰椎疾病的斜外侧椎间融合术的疗效

Outcomes of oblique lateral interbody fusion for degenerative lumbar disease in patients under or over 65 years of age.

作者信息

Jin Chengzhen, Jaiswal Milin S, Jeun Sin-Soo, Ryu Kyeong-Sik, Hur Jung-Woo, Kim Jin-Sung

机构信息

Spine Center, Department of Neurosurgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea, 222 Banpo-daero Seocho-gu, Seoul, 06591, Republic of Korea.

出版信息

J Orthop Surg Res. 2018 Feb 20;13(1):38. doi: 10.1186/s13018-018-0740-2.

Abstract

BACKGROUND

Oblique lateral interbody fusion (OLIF) offers the solution to problems of anterior lumbar interbody fusion (ALIF) and lateral lumbar interbody fusion (LLIF). However, OLIF technique for degenerative spinal diseases of elderly patients has been rarely reported. The objective of this study was to determine the clinical and radiological results of OLIF technique for degenerative spinal diseases in patients under or over 65 years of age.

METHODS

Sixty-three patients who underwent OLIF procedure were enrolled, including 29 patients who were less than 65 years of age and 34 patients who were over 65 years of age. Fusion rate, change of disc height and lumbar lordotic angle, Numeric Rating Scale (NRS), return to daily activity, patient's satisfaction rate (PSR), and Oswestry disability index (ODI) were used to assess clinical and functional outcomes.

RESULTS

The mean NRS scores for back and leg pain decreased, respectively, from 4.6 and 5.9 to 2.3 and 1.8 in the group A (less than 65 years) and from 4.5 and 6.8 to 2.6 and 2.2 in the group B (over 65 years) at the final follow-up period. The mean ODI scores improved from 48.4 to 24.0% in the group A and from 46.5 to 25.2% in the group B at the final follow-up period. In both groups, the NRS and ODI scores significantly changed preoperatively to postoperatively (p <  0.001). However, statistical analysis yielded no significant difference in postoperative NRS/ODI scores between two groups. In both groups, the changes in the disc height, segmental lordosis, and fusion rate between the preoperative and postoperative periods were significant. The amount of change between preoperative and postoperative disc height, segmental lordosis, and whole lumbar lordosis demonstrated significant intergroup differences (p <  0.05). Overall perioperative complications occurred in 8 of 29 (27.6%) patients in the group A and in 10 of 34 (29.4%) patients in the group B. In both groups, the major complication incidence was 0 and 3%, respectively.

CONCLUSION

Although there was the slightly high incidence of complication associated with high rate of co-morbidities in elderly patients, OLIF for degenerative lumbar diseases in elderly patients showed favorable clinical and radiological outcomes.

摘要

背景

斜外侧椎间融合术(OLIF)为解决前路腰椎椎间融合术(ALIF)和侧路腰椎椎间融合术(LLIF)的问题提供了方案。然而,针对老年患者退行性脊柱疾病的OLIF技术鲜有报道。本研究的目的是确定OLIF技术用于65岁及以下或65岁以上患者退行性脊柱疾病的临床和影像学结果。

方法

纳入63例行OLIF手术的患者,其中29例年龄小于65岁,34例年龄大于65岁。采用融合率、椎间盘高度和腰椎前凸角的变化、数字评分量表(NRS)、恢复日常活动情况、患者满意率(PSR)和Oswestry功能障碍指数(ODI)来评估临床和功能结果。

结果

在末次随访时,A组(年龄小于65岁)背痛和腿痛的平均NRS评分分别从4.6和5.9降至2.3和1.8,B组(年龄大于65岁)分别从4.5和6.8降至2.6和2.2。在末次随访时,A组的平均ODI评分从48.4%改善至24.0%,B组从46.5%改善至25.2%。两组患者术前至术后的NRS和ODI评分均有显著变化(p < 0.001)。然而,统计学分析显示两组术后NRS/ODI评分无显著差异。两组术前至术后的椎间盘高度、节段性前凸和融合率变化均显著。术前至术后椎间盘高度、节段性前凸和整个腰椎前凸的变化量显示出组间显著差异(p < 0.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6df4/5819281/45ad8f6bf10b/13018_2018_740_Fig1_HTML.jpg

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