Nasir Muhammad, Attique Khan Muhammad, Sharif Muhammad, Lali Ikram Ullah, Saba Tanzila, Iqbal Tassawar
COMSATS Institute of Information Technology, Wah Cantt, Pakistan.
Department of Computer Science and Engineering, HITEC University, Museum Road, Taxila.
Microsc Res Tech. 2018 Jun;81(6):528-543. doi: 10.1002/jemt.23009. Epub 2018 Feb 21.
Melanoma is the deadliest type of skin cancer with highest mortality rate. However, the annihilation in early stage implies a high survival rate therefore, it demands early diagnosis. The accustomed diagnosis methods are costly and cumbersome due to the involvement of experienced experts as well as the requirements for highly equipped environment. The recent advancements in computerized solutions for these diagnoses are highly promising with improved accuracy and efficiency. In this article, we proposed a method for the classification of melanoma and benign skin lesions. Our approach integrates preprocessing, lesion segmentation, features extraction, features selection, and classification. Preprocessing is executed in the context of hair removal by DullRazor, whereas lesion texture and color information are utilized to enhance the lesion contrast. In lesion segmentation, a hybrid technique has been implemented and results are fused using additive law of probability. Serial based method is applied subsequently that extracts and fuses the traits such as color, texture, and HOG (shape). The fused features are selected afterwards by implementing a novel Boltzman Entropy method. Finally, the selected features are classified by Support Vector Machine. The proposed method is evaluated on publically available data set PH2. Our approach has provided promising results of sensitivity 97.7%, specificity 96.7%, accuracy 97.5%, and F-score 97.5%, which are significantly better than the results of existing methods available on the same data set. The proposed method detects and classifies melanoma significantly good as compared to existing methods.
黑色素瘤是最致命的皮肤癌类型,死亡率最高。然而,早期消灭意味着高生存率,因此需要早期诊断。由于需要经验丰富的专家参与以及对高装备环境的要求,传统的诊断方法成本高且繁琐。计算机化诊断解决方案的最新进展前景广阔,具有更高的准确性和效率。在本文中,我们提出了一种黑色素瘤和良性皮肤病变的分类方法。我们的方法集成了预处理、病变分割、特征提取、特征选择和分类。预处理是在使用DullRazor去除毛发的背景下执行的,而病变纹理和颜色信息用于增强病变对比度。在病变分割中,实施了一种混合技术,并使用概率加法法则融合结果。随后应用基于序列的方法,提取并融合颜色、纹理和HOG(形状)等特征。之后通过实施一种新颖的玻尔兹曼熵方法选择融合特征。最后,通过支持向量机对所选特征进行分类。所提出的方法在公开可用的数据集PH2上进行了评估。我们的方法提供了有希望的结果,灵敏度为97.7%,特异性为96.7%,准确率为97.5%,F分数为97.5%,明显优于同一数据集上现有方法的结果。与现有方法相比,所提出的方法在检测和分类黑色素瘤方面表现显著良好。