Pain Expertise Centre, Erasmus MC-Sophia Children's Hospital, P.O. Box: Postbus 2060, 3000, CA, Rotterdam, The Netherlands.
Palliative Care Centre, Laurens Cadenza, Oosterhagen 239, 3078, CL, Rotterdam, The Netherlands.
BMC Palliat Care. 2018 Feb 21;17(1):34. doi: 10.1186/s12904-018-0280-x.
In palliative care, administration of opioids is often indispensable for pain treatment. Pain assessment may help recognize pain and guide treatment in non-communicative patients. In the Netherlands the Rotterdam Elderly Pain Observation Scale (REPOS) is recommended to this aim, but not yet validated. Therefore the objective of this study was to validate the REPOS in non-communicative or unconscious end-of-life patients.
In this observational study, the primary researcher applied the REPOS, while both the researcher and a nurse applied the Numeric Rating Scale (NRS). If possible, the patient in question applied the NRS as well. The NRS scores were compared with the REPOS scores to determine concurrent validity. REPOS scores obtained before and after a pain-reducing intervention were analysed to establish the scale's sensitivity to change.
A total of 183 REPOS observations in 100 patients were analysed. Almost 90% of patients had an advanced malignancy; observations were done a median of 3 days (IQR 1 to 13) before death. Internal consistency of the REPOS was 0.73. The Pearson product moment correlation coefficient ranged from 0.64 to 0.80 between REPOS and NRS scores. REPOS scores declined with median 2 points (IQR 1 to 4) after a pain-reducing intervention (p < 0.001). Optimal sensitivity (0.81) and specificity (0.62) were found at cut-off score 3.
This study demonstrates that the REPOS has promising psychometric properties for pain assessment in non-communicative end-of-life patients. Its application may be of additional value to relieve suffering, including pain, in palliative care.
在姑息治疗中,阿片类药物的管理通常是疼痛治疗不可或缺的。疼痛评估有助于识别疼痛,并指导非交流患者的治疗。在荷兰,推荐使用鹿特丹老年人疼痛观察量表(REPOS)来达到这一目的,但尚未得到验证。因此,本研究的目的是验证 REPOS 在非交流或无意识临终患者中的有效性。
在这项观察性研究中,主要研究者应用了 REPOS,同时研究者和一名护士也应用了数字评分量表(NRS)。如果可能的话,研究对象也应用了 NRS。将 NRS 评分与 REPOS 评分进行比较,以确定其同时效度。分析 REPOS 评分在疼痛减轻干预前后的变化,以确定该量表对变化的敏感性。
共分析了 100 名患者的 183 个 REPOS 观察结果。近 90%的患者患有晚期恶性肿瘤;观察在死亡前中位数为 3 天(IQR 1 至 13)进行。REPOS 的内部一致性为 0.73。REPOS 评分与 NRS 评分之间的 Pearson 积矩相关系数范围为 0.64 至 0.80。疼痛减轻干预后,REPOS 评分中位数下降 2 分(IQR 1 至 4)(p<0.001)。在截断值为 3 时,灵敏度(0.81)和特异性(0.62)最佳。
本研究表明,REPOS 具有有前途的心理测量学特性,可用于评估非交流临终患者的疼痛。在姑息治疗中,它的应用可能有助于减轻痛苦,包括疼痛。