Lemke Amy A, Hulick Peter J, Wake Dyson T, Wang Chi, Sereika Annette W, Yu Kristen Dilzell, Glaser Nicole S, Dunnenberger Henry M
Center for Personalized Medicine, NorthShore University HealthSystem, 1001 University Place, Suite 160, Evanston, IL 60201, USA.
Biostatistics & Research Informatics, NorthShore University HealthSystem, 1001 University Place, Suite 146, Evanston, IL 60201, USA.
Pharmacogenomics. 2018 Mar;19(4):321-331. doi: 10.2217/pgs-2017-0191. Epub 2018 Feb 22.
To assess patient perceptions and utilization of pharmacogenomics (PGx) testing in an integrated community health system.
Fifty-seven patients completed an online survey assessing their experiences with PGx testing offered through two methods: a designated PGx clinic or direct access in-home testing.
The majority of participants perceived PGx testing as helpful in their healthcare and reported understanding their results. Some had concerns about privacy and discrimination; most lacked familiarity with the Genetic Information Nondiscrimination Act. There were no significant differences in views between participants tested through either model.
Participants reported value in both methods of PGx testing. Patient experiences, understanding and result utilization will play an important role in informing future development and implementation of PGx programs.
评估患者对综合社区卫生系统中药理基因组学（PGx）检测的认知及使用情况。
57名患者完成了一项在线调查，评估他们通过两种方式进行PGx检测的经历：指定的PGx诊所或直接上门检测。
大多数参与者认为PGx检测对其医疗保健有帮助，并表示理解检测结果。一些人担心隐私和歧视问题；大多数人对《遗传信息非歧视法案》并不熟悉。两种检测模式的参与者之间的观点没有显著差异。
参与者报告称两种PGx检测方法都有价值。患者的经历、理解和结果应用将对PGx项目未来的发展和实施起到重要作用。
