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土耳其强直性脊柱炎患者人群中葡萄膜炎的临床特征和预后:眼部并发症的发生率和处理。

Clinical Features and Prognosis of Uveitis in a Turkish Patient Population with Ankylosing Spondylitis: Incidence and Management of Ocular Complications.

机构信息

a Department of Ophthalmology , Ankara Training and Research Hospital , Altindag , Turkey.

b Ophthalmology Clinic , Dr. Nafiz Korez Hospital , Sincan , Turkey.

出版信息

Ocul Immunol Inflamm. 2019;27(4):551-559. doi: 10.1080/09273948.2018.1431290. Epub 2018 Feb 23.

Abstract

: To investigate clinical features, visual prognosis, and ocular complications in patients with ankylosing spondylitis (AS)-associated anterior uveitis (AU). : Data of 211 eyes of 145 patients with AU associated with AS were reviewed retrospectively. : Mean follow-up time was 6.31 ± 6.33 years. Men were younger than women at AS diagnosis (= 0.035). The mean number of uveitis flares was highest during the first quarter of the year and lowest during the third quarter (= 0.017). Immunosuppressive agent use was higher in women than men (= 0.052). Ocular complications developed in 120 eyes (56.9%), and the complication rate was 0.146/eye year. Males developed cystoid macular edema more frequently than females (= 0.05). Glaucoma was observed more often in early-onset disease (age at AS onset <45 years) than late-onset disease (= 0.028). : Visual prognosis of AU in patients with AS was good, although more than half of the eyes developed ocular complications (56.9%).

摘要

目的

探讨强直性脊柱炎(AS)相关性前葡萄膜炎(AU)患者的临床特征、视力预后和眼部并发症。

方法

回顾性分析了 145 例 AU 患者 211 只眼的资料。平均随访时间为 6.31±6.33 年。AS 诊断时男性较女性年龄小(=0.035)。葡萄膜炎发作次数在第一季度最高,第三季度最低(=0.017)。女性免疫抑制剂的使用高于男性(=0.052)。120 只眼(56.9%)出现眼部并发症,并发症发生率为 0.146/眼年。男性发生囊样黄斑水肿的频率高于女性(=0.05)。早发型(AS 发病年龄<45 岁)疾病比晚发型(=0.028)更易发生青光眼。

结论

尽管超过一半的眼睛发生了眼部并发症(56.9%),但 AS 患者 AU 的视力预后良好。

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