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基于互联网的多领域干预设计用于预防老年人心血管疾病和认知障碍:HATICE 试验。

Designing an Internet-Based Multidomain Intervention for the Prevention of Cardiovascular Disease and Cognitive Impairment in Older Adults: The HATICE Trial.

机构信息

Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland.

Department of Neurobiology, Aging Research Center, Health Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

出版信息

J Alzheimers Dis. 2018;62(2):649-663. doi: 10.3233/JAD-170858.

Abstract

BACKGROUND

Many dementia and cardiovascular disease (CVD) cases in older adults are attributable to modifiable vascular and lifestyle-related risk factors, providing opportunities for prevention. In the Healthy Aging Through Internet Counselling in the Elderly (HATICE) randomized controlled trial, an internet-based multidomain intervention is being tested to improve the cardiovascular risk (CVR) profile of older adults.

OBJECTIVE

To design a multidomain intervention to improve CVR, based on the guidelines for CVR management, and administered through a coach-supported, interactive, platform to over 2500 community-dwellers aged 65+ in three European countries.

METHODS

A comparative analysis of national and European guidelines for primary and secondary CVD prevention was performed. Results were used to define the content of the intervention.

RESULTS

The intervention design focused on promoting awareness and self-management of hypertension, dyslipidemia, diabetes mellitus, and overweight, and supporting smoking cessation, physical activity, and healthy diet. Overall, available guidelines lacked specific recommendations for CVR management in older adults. The comparative analysis of the guidelines showed general consistency for lifestyle-related recommendations. Key differences, identified mostly in methods used to assess the overall CVR, did not hamper the intervention design. Minor country-specific adaptations were implemented to maximize the intervention feasibility in each country.

CONCLUSION

Despite differences in CVR management within the countries considered, it was possible to design and implement the HATICE multidomain intervention. The study can help define preventative strategies for dementia and CVD that are applicable internationally.

摘要

背景

许多老年人的痴呆症和心血管疾病(CVD)病例可归因于可改变的血管和与生活方式相关的风险因素,为预防提供了机会。在“通过老年人互联网咨询促进健康老龄化(HATICE)”随机对照试验中,正在测试一种基于心血管风险(CVR)管理指南的基于互联网的多领域干预措施,以改善老年人的心血管风险(CVR)状况。

目的

根据心血管疾病初级和二级预防的国家和欧洲指南,设计一项多领域干预措施,以改善 CVR,并通过教练支持、互动式平台为三个欧洲国家的 2500 多名 65 岁以上的社区居民提供干预措施。

方法

对国家和欧洲初级和二级 CVD 预防指南进行了比较分析。将结果用于定义干预内容。

结果

干预设计侧重于提高对高血压、血脂异常、糖尿病和超重的认识和自我管理水平,并支持戒烟、身体活动和健康饮食。总的来说,现有的指南缺乏针对老年人 CVR 管理的具体建议。指南的比较分析表明,与生活方式相关的建议具有普遍一致性。确定的主要差异主要在于评估总体 CVR 所使用的方法,但这并没有妨碍干预设计。针对每个国家实施了一些较小的特定于国家的调整,以最大限度地提高每个国家的干预可行性。

结论

尽管所考虑的国家在 CVR 管理方面存在差异,但仍有可能设计和实施 HATICE 多领域干预措施。该研究可以帮助确定适用于国际的痴呆症和 CVD 的预防策略。

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