School of Chemical Engineering, College of Engineering, University of Tehran, Tehran, Iran.
Department of Chemistry, Amirkabir University of Technology, Tehran, Iran.
Carbohydr Polym. 2018 May 1;187:66-84. doi: 10.1016/j.carbpol.2018.01.060. Epub 2018 Jan 31.
Agarose is a natural polysaccharide polymer having unique characteristics that give reason to consider it for tissue engineering applications. Special characteristics of agarose such as its excellent biocompatibility, thermo-reversible gelation behavior and physiochemical features support its use as a biomaterial for cell growth and/or controlled/localized drug delivery. The resemblance of this natural carbohydrate polymer to the extracellular matrix results in attractive features that bring about a strong interest in its usage in the field. The scope of this review is to summarize the extensive researches addressing agarose-based biomaterials in order to provide an in-depth understanding of its tissue engineering-related applications.
琼脂糖是一种天然多糖聚合物，具有独特的特性，使其成为组织工程应用的理想选择。琼脂糖的特殊特性，如出色的生物相容性、热可逆凝胶行为和物理化学特性，支持其作为细胞生长和/或控制/局部药物输送的生物材料的应用。这种天然碳水化合物聚合物与细胞外基质的相似性带来了吸引人的特性，使其在该领域的应用受到强烈关注。本文综述了基于琼脂糖的生物材料的广泛研究，旨在深入了解其与组织工程相关的应用。
