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个性化医疗与适当剂量：慢性病的过度与不足治疗危及患者健康并加重公共卫生系统负担。

Personalized medicine and proper dosage: Over- and undertreatment of chronic diseases endanger patients' health and strain public health systems.

机构信息

Heidelberg, Germany.

出版信息

EMBO Rep. 2018 Apr;19(4). doi: 10.15252/embr.201845957. Epub 2018 Feb 27.

DOI:10.15252/embr.201845957
PMID:29487086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5891408/
Abstract

Improper treatment of common diseases and conditions endangers patients’ health and wastes enormous public resources. Better clinical trial data and more personalized treatment of these conditions could greatly improve health and health care. [Image: see text]

摘要

不当治疗常见疾病和病症会危害患者健康并浪费大量公共资源。更好的临床试验数据和对这些病症的更个性化治疗可以极大地改善健康和医疗保健。[图片：见正文]

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J Gen Intern Med. 2018 Jan;33(1):34-41. doi: 10.1007/s11606-017-4167-y. Epub 2017 Sep 13.
3
Overtreatment in the United States.美国的过度治疗。
PLoS One. 2017 Sep 6;12(9):e0181970. doi: 10.1371/journal.pone.0181970. eCollection 2017.
4
Survival Benefits of Statins for Primary Prevention: A Cohort Study.他汀类药物用于一级预防的生存获益：一项队列研究。
PLoS One. 2016 Nov 18;11(11):e0166847. doi: 10.1371/journal.pone.0166847. eCollection 2016.
5
Is there a risk in overtreating a hypertensive patient?过度治疗高血压患者存在风险吗？
J Cardiovasc Med (Hagerstown). 2017 Jan;18 Suppl 1:e50-e53. doi: 10.2459/JCM.0000000000000440.
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Recent Update to the US Cholesterol Treatment Guidelines: A Comparison With International Guidelines.美国胆固醇治疗指南的最新更新：与国际指南的比较
Circulation. 2016 May 3;133(18):1795-806. doi: 10.1161/CIRCULATIONAHA.116.021407.
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Development of the Tool to Reduce Inappropriate Medications (TRIM): A Clinical Decision Support System to Improve Medication Prescribing for Older Adults.减少不适当用药工具（TRIM）的开发：一种改善老年人用药处方的临床决策支持系统。
Pharmacotherapy. 2016 Jun;36(6):694-701. doi: 10.1002/phar.1751. Epub 2016 May 28.
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