Kumar K Jagadish, Ashok Chowdary K V, Usha H C, Kulkarni Maduri, Manjunath V G
Department of Pediatrics, JSS Medical College, JSS University, Mysore, Karnataka, India.
Department of Microbiology, JSS Medical College, JSS University, Mysore, Karnataka, India.
Lung India. 2018 Mar-Apr;35(2):116-120. doi: 10.4103/lungindia.lungindia_391_16.
The aim is to identify the etiology of community acquired pneumonia in children with special reference to atypical bacteria and viruses.
A total of 94 pneumonia children were enrolled in the study. Sixty-seven did not have an etiological diagnosis by conventional culture. These children were subjected to immunofluorescence assay by Pneumoslide IgM.
Ninety-four children were evaluated for etiology by conventional culture. Twenty-seven of them had the bacteriological diagnosis. Rest 67 were further analyzed for causative organism using Pneumoslide immunofluorescence test. Among this group, 38 (56.7%) had etiological diagnosis. Atypical bacteria were identified in 23 cases, most common being Mycoplasma pneumoniae and which was more common between 5 months and 2 years of age. Viruses were identified in 19 cases, and the most common virus was Respiratory syncytial virus. Mixed pathogens were identified in five children., M. pneumoniae was the common offending agent.
Atypical bacteria and viruses play an important role as etiological agents in pneumonia in children. Pneumoslide IgM is useful for rapid detection of atypical bacteria and viruses.
旨在确定儿童社区获得性肺炎的病因,特别关注非典型细菌和病毒。
共有94名肺炎患儿纳入本研究。67名患儿通过传统培养未获得病因诊断。这些患儿接受了肺炎支原体IgM免疫荧光检测。
94名患儿通过传统培养评估病因。其中27名获得细菌学诊断。其余67名使用肺炎支原体免疫荧光试验进一步分析病原体。在这组患儿中,38名(56.7%)获得病因诊断。23例鉴定出非典型细菌,最常见的是肺炎支原体,在5个月至2岁儿童中更为常见。19例鉴定出病毒,最常见的病毒是呼吸道合胞病毒。5名儿童鉴定出混合病原体,肺炎支原体是常见的致病原。
非典型细菌和病毒在儿童肺炎病因中起重要作用。肺炎支原体IgM对快速检测非典型细菌和病毒有用。