El Kettani Assiya, Maaloum Fakhreddine, Diawara Idrissa, Katfy Khalid, Harrar Nadia, Zerouali Khalid, Belabbes Houria, Elmdaghri Naima
Department of Microbiology, Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Morocco.
Bacteriology-Virology and Hospital Hygiene Laboratory, University Hospital Centre Ibn Rochd of Casablanca, Morocco.
Iran J Microbiol. 2017 Dec;9(6):318-323.
bacteremia are grave because of the multi-resistance of the organism to antibiotics. This study aimed to determine the prevalence of isolated from blood cultures and to describe their antibiotic resistance patterns.
A retrospective longitudinal study was conducted on blood cultures between 2010 and 2014 from all Ibn Rochd University Hospital intensive care units; it was based on the exploitation of microbiology laboratory database (duplicates were excluded). Isolation and identification of were performed according to standard techniques of bacteriology and susceptibility testing as recommended by the CLSI. PCR was used to detect β-Lactamase genes, , .
Among the 4232 samples received at the laboratory, 2402 (56.8%) were positive. Negative coagulase was isolated in 21.6% of cases followed by (9.2%), and (9.1%). strains were resistant to most antibiotics tested: imipenem (75.7%), ceftazidim (85.4%), cefotaxim (98.6%), gentamicin (78.1%), amikacin (63.5%) and ciprofloxacin (88.2%). All strains, resistant to carbapenem, tested were positive for genes and 87.5% expressed the genes.
was the second germ frequently isolated from blood cultures in intensive care units. It was multi-resistant to antibiotics. The strengthening of hospital hygiene measures and surveillance of antibiotic resistance is needed to limit the spread of germs and to optimize the management of antibiotics.
由于该生物体对多种抗生素耐药,菌血症病情严重。本研究旨在确定从血培养中分离出的[细菌名称未明确]的患病率,并描述其抗生素耐药模式。
对2010年至2014年伊本·罗什德大学医院所有重症监护病房的血培养进行回顾性纵向研究;该研究基于微生物学实验室数据库的利用(排除重复样本)。[细菌名称未明确]的分离和鉴定按照细菌学标准技术及CLSI推荐的药敏试验进行。采用PCR检测β-内酰胺酶基因,[具体基因未明确]。
在实验室收到的4232份样本中,2402份(56.8%)呈阳性。凝固酶阴性葡萄球菌在21.6%的病例中分离得到,其次是[细菌名称未明确](9.2%)和[细菌名称未明确](9.1%)。[细菌名称未明确]菌株对大多数测试抗生素耐药:亚胺培南(75.7%)、头孢他啶(85.4%)、头孢噻肟(98.6%)、庆大霉素(78.1%)、阿米卡星(63.5%)和环丙沙星(88.2%)。所有对碳青霉烯耐药的[细菌名称未明确]菌株,检测均为[具体基因未明确]基因阳性,87.5%表达[具体基因未明确]基因。
[细菌名称未明确]是重症监护病房血培养中第二常见分离出的细菌。它对多种抗生素耐药。需要加强医院卫生措施及抗生素耐药监测,以限制病菌传播并优化抗生素管理。