Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom.
Nuffield Department of Obstetrics & Gynaecology, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.
PLoS One. 2018 Feb 28;13(2):e0193406. doi: 10.1371/journal.pone.0193406. eCollection 2018.
The INTER-NDA is a novel assessment of early child development measuring cognition, language, motor skills, behaviour, attention, and socio-emotional reactivity in 2 year olds in 15 minutes. Here, we present the results of an evaluation of the INTER-NDA against the Bayley Scales of Infant Development III edition (BSID-III), its sensitivity and specificity and its psychometric properties.
Eighty-one infants from Oxford, UK, aged 23.1-28.3 months, were evaluated using the INTER-NDA and the BSID-III. The agreement between the INTER-NDA and the BSID-III was assessed using interclass correlations (for absolute agreement), Bland-Altman analyses (for bias and limits of agreement), and sensitivity and specificity analyses (for accuracy). The internal consistency of the INTER-NDA and uni-dimensionality of its subscales were also determined.
The interclass correlation coefficients between the BSID-III and the INTER-NDA cognitive, motor and behaviour scores ranged between 0.745 and 0.883 (p<0.001). The Bland-Altman analysis showed little to no bias in the aforementioned subscales. The sensitivity and specificity of INTER-NDA cognitive scores ≤1 SD below the mean are 66.7% and 98.6% respectively, with moderate agreement between INTER-NDA and BSID-III classifications (κ = 0.72, p<0.001). The sensitivity and specificity of INTER-NDA scores <2 SD below the mean, in predicting low BSID-III scores (<70), are 100% each for cognition, and 25% and 100% respectively for language. More than 97% of children who scored in the normal range of the INTER-NDA (<1SD below mean) also scored in the normal range in the BSID-III (≥85). The INTER-NDA demonstrates satisfactory internal consistency and its subscales demonstrate good unidimensionality.
The INTER-NDA shows good agreement with the BSID-III, and demonstrates satisfactory psychometric properties, for the assessment of ECD at 22-28 months.
INTER-NDA 是一种新颖的儿童早期发育评估方法，可在 15 分钟内测量 2 岁儿童的认知、语言、运动技能、行为、注意力和社会情感反应。在这里，我们介绍了 INTER-NDA 与贝利婴幼儿发展量表第三版（BSID-III）的评估结果，包括其敏感性和特异性以及心理测量特性。
81 名来自英国牛津的婴儿年龄为 23.1-28.3 个月，使用 INTER-NDA 和 BSID-III 进行评估。使用组内相关系数（用于绝对一致性）、Bland-Altman 分析（用于偏差和一致性界限）以及敏感性和特异性分析（用于准确性）评估 INTER-NDA 和 BSID-III 之间的一致性。还确定了 INTER-NDA 的内部一致性和其子量表的单维性。
BSID-III 和 INTER-NDA 认知、运动和行为评分之间的组内相关系数在 0.745 到 0.883 之间（p<0.001）。Bland-Altman 分析显示上述子量表几乎没有偏差。INTER-NDA 认知评分低于平均值 1 个标准差的敏感性和特异性分别为 66.7%和 98.6%，INTER-NDA 和 BSID-III 分类之间具有中度一致性（κ=0.72，p<0.001）。INTER-NDA 评分低于平均值 2 个标准差，预测 BSID-III 评分较低（<70）的敏感性和特异性分别为 100%，语言分别为 25%和 100%。在 INTER-NDA 正常范围内（低于平均值 1 个标准差）得分的儿童中，超过 97%的儿童在 BSID-III 中也在正常范围内（≥85）。INTER-NDA 具有令人满意的内部一致性，其子量表具有良好的单维性。
INTER-NDA 与 BSID-III 具有良好的一致性，并具有令人满意的心理测量特性，可用于评估 22-28 个月儿童的 ECD。
