Regulating Renewable Energy: Connecting AMPKα2 to PINK1/Parkin-Mediated Mitophagy in the Heart.
作者信息
Shires Sarah E, Gustafsson Åsa B
机构信息
From the Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacology, University of California San Diego, La Jolla.
出版信息
Circ Res. 2018 Mar 2;122(5):649-651. doi: 10.1161/CIRCRESAHA.118.312655.
Abstract
摘要
相似文献
1
Regulating Renewable Energy: Connecting AMPKα2 to PINK1/Parkin-Mediated Mitophagy in the Heart.
Circ Res. 2018 Mar 2;122(5):649-651. doi: 10.1161/CIRCRESAHA.118.312655.
2
AMPKα2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation.
Circ Res. 2018 Mar 2;122(5):712-729. doi: 10.1161/CIRCRESAHA.117.312317. Epub 2017 Dec 28.
3
PINK1/Parkin-mediated mitophagy in mammalian cells.
Curr Opin Cell Biol. 2015 Apr;33:95-101. doi: 10.1016/j.ceb.2015.01.002. Epub 2015 Feb 17.
4
Deciphering the Molecular Signals of PINK1/Parkin Mitophagy.
Trends Cell Biol. 2016 Oct;26(10):733-744. doi: 10.1016/j.tcb.2016.05.008. Epub 2016 Jun 10.
5
The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications.
Genes Dev. 2015 May 15;29(10):989-99. doi: 10.1101/gad.262758.115.
6
Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy.
Proc Natl Acad Sci U S A. 2015 May 26;112(21):6637-42. doi: 10.1073/pnas.1506593112. Epub 2015 May 12.
7
Mechanisms of mitophagy: PINK1, Parkin, USP30 and beyond.
Free Radic Biol Med. 2016 Nov;100:210-222. doi: 10.1016/j.freeradbiomed.2016.04.015. Epub 2016 Apr 16.
8
Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway.
Toxicol In Vitro. 2018 Sep;51:1-10. doi: 10.1016/j.tiv.2018.05.001. Epub 2018 May 3.
9
PGAM5 regulates PINK1/Parkin-mediated mitophagy via DRP1 in CCCP-induced mitochondrial dysfunction.
Toxicol Lett. 2018 Mar 1;284:120-128. doi: 10.1016/j.toxlet.2017.12.004. Epub 2017 Dec 11.
10
Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility.
Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6097-E6106. doi: 10.1073/pnas.1612283113. Epub 2016 Sep 27.
引用本文的文献
1
Dapagliflozin Alleviates Myocardial Ischaemia Reperfusion Injury by Activating Mitophagy the AMPK-PINK1/Parkin Signalling Pathway.
Curr Vasc Pharmacol. 2024;22(3):203-217. doi: 10.2174/0115701611269801231211104905.
2
Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy.
JACC Basic Transl Sci. 2023 Jul 19;8(9):1215-1239. doi: 10.1016/j.jacbts.2023.04.006. eCollection 2023 Sep.
3
Protective Effect of Natural Medicinal Plants on Cardiomyocyte Injury in Heart Failure: Targeting the Dysregulation of Mitochondrial Homeostasis and Mitophagy.
Oxid Med Cell Longev. 2022 Sep 12;2022:3617086. doi: 10.1155/2022/3617086. eCollection 2022.
4
Ubiquitinated AIF is a major mediator of hypoxia-induced mitochondrial dysfunction and pulmonary artery smooth muscle cell proliferation.
Cell Biosci. 2022 Jan 28;12(1):9. doi: 10.1186/s13578-022-00744-3.
5
Targeting PINK1 Using Natural Products for the Treatment of Human Diseases.
Biomed Res Int. 2021 Oct 30;2021:4045819. doi: 10.1155/2021/4045819. eCollection 2021.
6
Mitophagy in Human Diseases.
Int J Mol Sci. 2021 Apr 9;22(8):3903. doi: 10.3390/ijms22083903.
7
Barth syndrome cardiomyopathy: targeting the mitochondria with elamipretide.
Heart Fail Rev. 2021 Mar;26(2):237-253. doi: 10.1007/s10741-020-10031-3. Epub 2020 Oct 1.
8
AMPKα2 Overexpression Reduces Cardiomyocyte Ischemia-Reperfusion Injury Through Normalization of Mitochondrial Dynamics.
Front Cell Dev Biol. 2020 Aug 27;8:833. doi: 10.3389/fcell.2020.00833. eCollection 2020.
9
Cadmium induces mitophagy via AMP-activated protein kinases activation in a PINK1/Parkin-dependent manner in PC12 cells.
Cell Prolif. 2020 Jun;53(6):e12817. doi: 10.1111/cpr.12817. Epub 2020 May 12.
10
Role of Mitophagy in Cardiovascular Disease.
Aging Dis. 2020 Mar 9;11(2):419-437. doi: 10.14336/AD.2019.0518. eCollection 2020 Apr.
本文引用的文献
1
PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol.
BMC Biol. 2018 Jan 10;16(1):2. doi: 10.1186/s12915-017-0470-7.
2
AMPKα2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation.
Circ Res. 2018 Mar 2;122(5):712-729. doi: 10.1161/CIRCRESAHA.117.312317. Epub 2017 Dec 28.
3
AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System.
Circ Res. 2017 May 26;120(11):1825-1841. doi: 10.1161/CIRCRESAHA.117.309633.
4
Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure.
Circulation. 2016 Mar 29;133(13):1249-63. doi: 10.1161/CIRCULATIONAHA.115.020502. Epub 2016 Feb 25.
5
Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice.
Science. 2015 Dec 4;350(6265):aad2459. doi: 10.1126/science.aad2459. Epub 2015 Dec 3.
6
Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury.
PLoS One. 2013 Apr 29;8(4):e62400. doi: 10.1371/journal.pone.0062400. Print 2013.
7
Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction.
J Biol Chem. 2013 Jan 11;288(2):915-26. doi: 10.1074/jbc.M112.411363. Epub 2012 Nov 14.
8
Mitochondria and mitophagy: the yin and yang of cell death control.
Circ Res. 2012 Oct 12;111(9):1208-21. doi: 10.1161/CIRCRESAHA.112.265819.
9
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
PLoS Biol. 2010 Jan 26;8(1):e1000298. doi: 10.1371/journal.pbio.1000298.
10
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.
Nature. 2006 Jun 29;441(7097):1162-6. doi: 10.1038/nature04779. Epub 2006 May 3.
Zotero 插件