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Induced Pluripotent Stem Cell (iPSC)-Derived Exosomes for Precision Medicine in Heart Failure.

作者信息

Yang Phillip C

机构信息

From the Division of Cardiovascular Medicine, Department of Medicine and Cardiovascular Institute, Stanford University School of Medicine, CA.

出版信息

Circ Res. 2018 Mar 2;122(5):661-663. doi: 10.1161/CIRCRESAHA.118.312657.

DOI:10.1161/CIRCRESAHA.118.312657
PMID:29496797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5836744/
Abstract
摘要

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本文引用的文献

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Exosomes Generated From iPSC-Derivatives: New Direction for Stem Cell Therapy in Human Heart Diseases.源自诱导多能干细胞衍生物的外泌体：人类心脏病干细胞治疗的新方向。
Circ Res. 2017 Jan 20;120(2):407-417. doi: 10.1161/CIRCRESAHA.116.309307.
2
Epicardial FSTL1 reconstitution regenerates the adult mammalian heart.心外膜FSTL1重建可使成年哺乳动物心脏再生。
Nature. 2015 Sep 24;525(7570):479-85. doi: 10.1038/nature15372. Epub 2015 Sep 16.
3
Manganese-Enhanced Magnetic Resonance Imaging Enables In Vivo Confirmation of Peri-Infarct Restoration Following Stem Cell Therapy in a Porcine Ischemia-Reperfusion Model.
基因工程化的人类诱导多能干细胞用于生产靶向大脑的细胞外囊泡。
Stem Cell Res Ther. 2024 Oct 8;15(1):345. doi: 10.1186/s13287-024-03955-2.
4
Unlocking cardioprotection: iPSC exosomes deliver Nec-1 to target PARP1/AIFM1 axis, alleviating HF oxidative stress and mitochondrial dysfunction.解锁心脏保护：iPSC 外泌体传递 Nec-1 至靶标 PARP1/AIFM1 轴，减轻 HF 氧化应激和线粒体功能障碍。
J Transl Med. 2024 Jul 26;22(1):681. doi: 10.1186/s12967-024-05204-9.
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Plasma-derived extracellular vesicles improve mice embryo development.血浆衍生的细胞外囊泡可改善胚胎发育。
Mol Biol Rep. 2024 May 6;51(1):621. doi: 10.1007/s11033-024-09500-x.
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3D bioprinted aged human post-infarct myocardium tissue model.3D生物打印的老年人心肌梗死后组织模型
Health Sci Rep. 2024 Apr 22;7(4):e1945. doi: 10.1002/hsr2.1945. eCollection 2024 Apr.
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Urine-derived stem cells: Promising advancements and applications in regenerative medicine and beyond.尿液来源的干细胞：再生医学及其他领域的前景进展与应用
Heliyon. 2024 Mar 10;10(6):e27306. doi: 10.1016/j.heliyon.2024.e27306. eCollection 2024 Mar 30.
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Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes.间充质干细胞外泌体调节的缺血性小鼠心脏改变中涉及的转录因子的蛋白质组学分析。
Biochem Biophys Rep. 2023 Apr 14;34:101463. doi: 10.1016/j.bbrep.2023.101463. eCollection 2023 Jul.
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Induced pluripotent stem cells as natural biofactories for exosomes carrying miR-199b-5p in the treatment of spinal cord injury.诱导多能干细胞作为携带miR-199b-5p的外泌体治疗脊髓损伤的天然生物工厂。
Front Pharmacol. 2023 Jan 10;13:1078761. doi: 10.3389/fphar.2022.1078761. eCollection 2022.
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Theranostics. 2022 Oct 31;12(17):7550-7566. doi: 10.7150/thno.77630. eCollection 2022.
锰增强磁共振成像可在猪缺血再灌注模型中对干细胞治疗后梗死周围组织恢复情况进行体内确认。
J Am Heart Assoc. 2015 Jul 27;4(7):e002044. doi: 10.1161/JAHA.115.002044.
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Direct evaluation of myocardial viability and stem cell engraftment demonstrates salvage of the injured myocardium.对心肌活力和干细胞植入的直接评估显示受损心肌得以挽救。
Circ Res. 2015 Mar 27;116(7):e40-50. doi: 10.1161/CIRCRESAHA.116.304668. Epub 2015 Feb 5.
5
Heart disease and stroke statistics--2015 update: a report from the American Heart Association.《2015年心脏病和中风统计数据更新：美国心脏协会报告》
Circulation. 2015 Jan 27;131(4):e29-322. doi: 10.1161/CIR.0000000000000152. Epub 2014 Dec 17.
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The relationship between hospital admission rates and rehospitalizations.医院入院率与再入院率之间的关系。
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Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial.缺血性心肌病患者的心脏干细胞（SCIPIO）：一项随机 1 期试验的初步结果。
Lancet. 2011 Nov 26;378(9806):1847-57. doi: 10.1016/S0140-6736(11)61590-0. Epub 2011 Nov 14.
8
Dual manganese-enhanced and delayed gadolinium-enhanced MRI detects myocardial border zone injury in a pig ischemia-reperfusion model.双重锰增强和延迟钆增强 MRI 检测猪缺血再灌注模型中心肌边缘带损伤。
Circ Cardiovasc Imaging. 2011 Sep;4(5):574-82. doi: 10.1161/CIRCIMAGING.110.960591. Epub 2011 Jun 30.
9
Quantitative tissue characterization of infarct core and border zone in patients with ischemic cardiomyopathy by magnetic resonance is associated with future cardiovascular events.磁共振定量组织特征分析可用于评估缺血性心肌病患者的梗死核心和边缘带，与未来心血管事件相关。
J Am Coll Cardiol. 2010 Jun 15;55(24):2762-8. doi: 10.1016/j.jacc.2010.01.052.
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Quantitative characterization of myocardial infarction by cardiovascular magnetic resonance predicts future cardiovascular events in patients with ischemic cardiomyopathy.心血管磁共振对心肌梗死的定量表征可预测缺血性心肌病患者未来的心血管事件。
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